Suppr超能文献

心室心脏网格的个性化自动服务。

An automatic service for the personalization of ventricular cardiac meshes.

机构信息

Department of Biomedical Engineering, King's College of London, St Thomas' Hospital, , London SE1 7EH, UK.

出版信息

J R Soc Interface. 2013 Dec 11;11(91):20131023. doi: 10.1098/rsif.2013.1023. Print 2014 Feb 6.

Abstract

Computational cardiac physiology has great potential to improve the management of cardiovascular diseases. One of the main bottlenecks in this field is the customization of the computational model to the anatomical and physiological status of the patient. We present a fully automatic service for the geometrical personalization of cardiac ventricular meshes with high-order interpolation from segmented images. The method is versatile (able to work with different species and disease conditions) and robust (fully automatic results fulfilling accuracy and quality requirements in 87% of 255 cases). Results also illustrate the capability to minimize the impact of segmentation errors, to overcome the sparse resolution of dynamic studies and to remove the sometimes unnecessary anatomical detail of papillary and trabecular structures. The smooth meshes produced can be used to simulate cardiac function, and in particular mechanics, or can be used as diagnostic descriptors of anatomical shape by cardiologists. This fully automatic service is deployed in a cloud infrastructure, and has been made available and accessible to the scientific community.

摘要

计算心脏生理学具有改善心血管疾病管理的巨大潜力。该领域的主要瓶颈之一是将计算模型定制到患者的解剖和生理状态。我们提出了一种完全自动化的服务,用于从分割图像进行心脏心室网格的高次插值的几何个性化。该方法具有通用性(能够用于不同物种和疾病状况)和鲁棒性(87%的 255 个案例中,全自动结果满足准确性和质量要求)。结果还说明了最小化分割错误影响、克服动态研究稀疏分辨率以及去除有时不必要的乳头肌和小梁结构解剖细节的能力。生成的平滑网格可用于模拟心脏功能,特别是力学,或者可作为心脏病学家诊断解剖形状的描述符。这种全自动服务部署在云计算基础设施中,并向科学界开放和提供。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c9c4/3869175/08d4d3000a32/rsif20131023-g1.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验