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巴西女性通常自行采用基于生物的疗法来治疗晚期乳腺癌或其症状。

Biologically based therapies are commonly self-prescribed by Brazilian women for the treatment of advanced breast cancer or its symptoms.

作者信息

Alfano Ana Camila Callado, Paiva Carlos Eduardo, Rugno Fernanda Capella, da Silva Raquel Haas, Paiva Bianca Sakamoto Ribeiro

机构信息

Clinical Research Unit, Barretos Cancer Hospital, Barretos, São Paulo, Brazil.

出版信息

Support Care Cancer. 2014 May;22(5):1303-11. doi: 10.1007/s00520-013-2087-x. Epub 2013 Dec 17.

Abstract

PURPOSE

Breast cancer (BC) might be associated with loss of function in affected patients, with a direct impact on their quality of life (QOL). Many women with metastatic BC seek relief of symptoms, including the use of complementary and alternative medicine (CAM) to cure cancer. The present study aimed to identify the pattern of CAM used by patients with metastatic BC and to assess the correlation between CAM use and scores on anxiety, depression, and QOL scales.

METHODS

A total of 126 women with metastatic BC were interviewed using four instruments: (1) a questionnaire containing socioeconomic, clinical, and demographic data and CAM use; (2) European Organization for Research and Treatment of Cancer Core Quality of Life Questionnaire (EORTC QLQ)-C30; (3) EORTC QLQ-BR23; and (4) the Hospital Anxiety and Depression Scale.

RESULTS

Fifty percent of the participants reported the use of at least one CAM modality. Biologically based practices were the most frequently used to treat BC and/or its symptoms, the most commonly discussed with the oncologists, and one of the CAM categories in which more patients reported a desire to learn more about. The overall use of CAM was not correlated with the scores on the anxiety, depression, and QOL scales. However, analysis of the association of the QOL scores with specific CAM modalities revealed some potential associations (especially for food supplements, art therapy, psychotherapy, and prayer).

CONCLUSIONS

Women with metastatic BC frequently make use of CAM to treat the cancer and/or its symptoms. Biologically based practices seem to be particularly important in Brazil. An association between specific CAM modalities and some QOL domains was suggested, but it needs further confirmation.

摘要

目的

乳腺癌(BC)可能会导致患病女性功能丧失,直接影响其生活质量(QOL)。许多转移性乳腺癌女性寻求症状缓解,包括使用补充和替代医学(CAM)来治愈癌症。本研究旨在确定转移性乳腺癌患者使用CAM的模式,并评估CAM使用与焦虑、抑郁和生活质量量表得分之间的相关性。

方法

使用四种工具对总共126名转移性乳腺癌女性进行访谈:(1)一份包含社会经济、临床和人口统计学数据以及CAM使用情况的问卷;(2)欧洲癌症研究与治疗组织核心生活质量问卷(EORTC QLQ)-C30;(3)EORTC QLQ-BR23;以及(4)医院焦虑和抑郁量表。

结果

50%的参与者报告使用了至少一种CAM方式。基于生物的疗法是治疗BC和/或其症状最常用的方法,是与肿瘤学家讨论最多的方法,也是更多患者表示希望了解更多信息的CAM类别之一。CAM的总体使用与焦虑、抑郁和生活质量量表得分无关。然而,对生活质量得分与特定CAM方式之间关联的分析揭示了一些潜在关联(特别是对于食品补充剂、艺术疗法、心理治疗和祈祷)。

结论

转移性乳腺癌女性经常使用CAM来治疗癌症和/或其症状。在巴西,基于生物的疗法似乎尤为重要。特定CAM方式与一些生活质量领域之间存在关联,但需要进一步证实。

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