Mbowe Omar, Diaz Alicia, Wallace Jana, Mazariegos Manolo, Jolly Pauline
Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, 1665 University Boulevard, RPHB 217, Birmingham, AL, 35294-0022, USA.
Matern Child Health J. 2014 Sep;18(7):1619-27. doi: 10.1007/s10995-013-1402-y.
Guatemala is experiencing a nutritional and lifestyle transition. While chronic malnutrition is prevalent, overweight, obesity and chronic diseases have increased substantially in the country. This study was conducted to investigate the prevalence of metabolic syndrome and the associated cardiovascular risk factors in the pre-adolescent Guatemalan population. A cross-sectional study was conducted among 302 Guatemalan children (8-13 years old) attending public and private schools in the Municipality of Chimaltenango. Demographic data and anthropometric and blood pressure measurements were collected. A blood sample was taken after an 8 h overnight fast and analyzed for glucose, triglyceride and high-density lipoprotein cholesterol levels. The data were analyzed to identify factors associated with metabolic syndrome and with its components. The prevalence of metabolic syndrome in the study population was 2.0 %. However, approximately 54 % of the children had at least one component of metabolic syndrome, while none had four or five of the components. The three most prevalent risk factors were high triglycerides (43.4 %), low HDL cholesterol (17.2 %) and obesity (12.3 %). Boys were more likely to be obese than girls and rural children were more likely to have higher triglyceride levels than urban children. Although the prevalence of metabolic syndrome is low, the fact that majority of the children already have at least one component of metabolic syndrome is cause for concern since components of metabolic syndrome can continue into adulthood and increase the risk for chronic diseases later in life. Therefore, immediate action should be taken to address the problem.
危地马拉正在经历营养和生活方式的转变。尽管慢性营养不良普遍存在,但该国超重、肥胖和慢性病的发病率已大幅上升。本研究旨在调查危地马拉青春期前人群中代谢综合征的患病率及其相关心血管危险因素。在奇马尔特南戈市公立和私立学校就读的302名危地马拉儿童(8 - 13岁)中开展了一项横断面研究。收集了人口统计学数据、人体测量数据和血压测量值。在禁食8小时过夜后采集血样,分析血糖、甘油三酯和高密度脂蛋白胆固醇水平。对数据进行分析,以确定与代谢综合征及其组成成分相关的因素。研究人群中代谢综合征的患病率为2.0%。然而,约54%的儿童至少有一项代谢综合征组成成分,而没有儿童有四项或五项组成成分。最常见的三个危险因素是高甘油三酯(43.4%)、低高密度脂蛋白胆固醇($17.2%$)和肥胖(12.3%)。男孩比女孩更易肥胖,农村儿童的甘油三酯水平比城市儿童更高。尽管代谢综合征的患病率较低,但大多数儿童已至少有一项代谢综合征组成成分这一事实令人担忧,因为代谢综合征的组成成分可能持续到成年期,并增加日后患慢性病的风险。因此,应立即采取行动解决该问题。