Department of Gastroenterology, Juntendo University, School of Medicine, Tokyo, Japan.
Department of Human Pathology, Juntendo University, School of Medicine, Tokyo, Japan.
Endoscopy. 2014 Feb;46(2):153-7. doi: 10.1055/s-0033-1359042. Epub 2013 Dec 11.
Gastric adenocarcinoma of the fundic gland (chief cell predominant type, GA-FG-CCP) was recently proposed as a new, rare variant of gastric adenocarcinoma. The aim of the current study was to evaluate the endoscopic features of GA-FG-CCP. A total of 10 GA-FG-CCPs were included and evaluated retrospectively. The endoscopic and clinicopathological features of the lesions were analyzed to provide information of diagnostic value. The GA-FG-CCPs were classified into two categories: submucosal tumor shape (60 %) and flat or depressed type (40 %). Endoscopically, the most common features were submucosal tumor shape (60 %), whitish color (70 %), dilated vessels with branching architecture (50 %), and background mucosa without atrophic change (90 %). GA-FG-CCP has distinct endoscopic characteristics, especially in terms of shape, color, vessels, and background mucosa and may be classified into two categories macroscopically. To diagnose GA-FG-CCP correctly by pathological examination of biopsy specimens, these endoscopic features should be taken into consideration.
胃底腺腺癌（主细胞优势型，GA-FG-CCP）是最近提出的一种新的罕见胃腺癌变体。本研究旨在评估 GA-FG-CCP 的内镜特征。共纳入 10 例 GA-FG-CCP 并进行回顾性分析。分析病变的内镜和临床病理特征，提供有诊断价值的信息。GA-FG-CCP 分为两类：黏膜下肿瘤形态（60%）和平坦或凹陷型（40%）。内镜下最常见的特征是黏膜下肿瘤形态（60%）、白色（70%）、分支状扩张血管（50%）和无萎缩性改变的背景黏膜（90%）。GA-FG-CCP 具有独特的内镜特征，尤其是在形态、颜色、血管和背景黏膜方面，可能在宏观上分为两类。为了通过活检病理检查正确诊断 GA-FG-CCP，应考虑这些内镜特征。
