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Quantitative systems pharmacology for shifting the drug discovery and development paradigm.

作者信息

Bai Jane P F

出版信息

Biopharm Drug Dispos. 2013 Dec;34(9):475-6. doi: 10.1002/bdd.1870.

DOI:10.1002/bdd.1870

PMID:24338789

Abstract

摘要

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相似文献

Quantitative systems pharmacology for shifting the drug discovery and development paradigm.

Biopharm Drug Dispos. 2013 Dec;34(9):475-6. doi: 10.1002/bdd.1870.

Integration not isolation: arguing the case for quantitative and systems pharmacology in drug discovery and development.

Drug Discov Today. 2011 Dec;16(23-24):1031-6. doi: 10.1016/j.drudis.2011.10.001. Epub 2011 Oct 13.

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Clin Pharmacol Ther. 2013 May;93(5):379-81. doi: 10.1038/clpt.2013.40.

[Network pharmacology and drug discovery].

Sheng Li Ke Xue Jin Zhan. 2011 Aug;42(4):241-5.

Systems pharmacology to predict drug toxicity: integration across levels of biological organization.

Annu Rev Pharmacol Toxicol. 2013;53:451-73. doi: 10.1146/annurev-pharmtox-011112-140248. Epub 2012 Nov 5.

Ligand-based approaches to in silico pharmacology.

Methods Mol Biol. 2011;672:489-502. doi: 10.1007/978-1-60761-839-3_19.

Modular pharmacology: deciphering the interacting structural organization of the targeted networks.

Drug Discov Today. 2013 Jun;18(11-12):560-6. doi: 10.1016/j.drudis.2013.01.009. Epub 2013 Jan 24.

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