Tan Chong Kiat, Yu Wesley Zongrong, Yeung Ying-Yeung
Department of Chemistry, National University of Singapore, Singapore.
Chirality. 2014 Jul;26(7):328-43. doi: 10.1002/chir.22272. Epub 2013 Dec 13.
The stereoselective bromofunctionalization of alkenes, particularly the enantioselective format, has been a subject of intense research in recent years. The ground-breaking works are documented in recent reviews. On the other hand, this account will provide an insight into our group's approach in tackling the challenges in enantioselective bromocyclization of alkenes as well as the development of diastereoselective N-bromosuccinimide-initiated multicomponent reactions.
烯烃的立体选择性溴官能团化，尤其是对映选择性形式，近年来一直是深入研究的课题。开创性的工作记录在最近的综述中。另一方面，本报告将深入探讨我们小组在应对烯烃对映选择性溴环化挑战以及非对映选择性N-溴代琥珀酰亚胺引发的多组分反应发展方面的方法。
