Panda Samhita, Sharma Kapil
Department of Clinical Neurophysiology, Sir Ganga Ram Hospital, New Delhi, India.
Ann Indian Acad Neurol. 2013 Oct;16(4):690-2. doi: 10.4103/0972-2327.120466.
Osteomalacia and rickets are important reversible causes of debilitating muscular weakness and bony pains in India among all socio-economic strata and at all ages. Osteomalacia after bariatric surgery is documented in literature. Most reports on osteomalacic weakness note myopathic pattern on electromyography. We present the case of a young obese girl from a good socio-economic status who developed severe muscular weakness after sleeve gastrectomy surgery. The patient was found to have osteomalacia with normal vitamin B12 and folate levels. Electrodiagnostic studies demonstrated neuropathic pattern while radiological tests confirmed osteopenia and Looser's zones. Specific vitamin D supplementation was associated with improvement though contribution of other micronutrients in diet cannot be ruled out. Relevance of vitamin D deficiency and urgent need for its correction in the population all over the world and especially in Asia is an emerging health issue. Peripheral motor neuropathy is a rare, seldom reported presentation of osteomalacia.
骨软化症和佝偻病是印度所有社会经济阶层及各年龄段导致使人衰弱的肌肉无力和骨痛的重要可逆性病因。文献中有关于减肥手术后发生骨软化症的记载。大多数关于骨软化性肌无力的报告指出肌电图显示肌病模式。我们报告了一名来自良好社会经济地位家庭的年轻肥胖女孩的病例,她在接受袖状胃切除术后出现了严重的肌肉无力。该患者被发现患有骨软化症,维生素B12和叶酸水平正常。电诊断研究显示为神经病变模式,而放射学检查证实有骨质减少和假骨折线。补充特定的维生素D虽有改善作用,但不能排除饮食中其他微量营养素的作用。维生素D缺乏的相关性以及在全世界尤其是亚洲人群中纠正维生素D缺乏的迫切需求是一个新出现的健康问题。周围性运动神经病是骨软化症一种罕见且鲜有报道的表现形式。