袖状胃切除术：减肥速度堪比微量营养素？
The gastric sleeve: losing weight as fast as micronutrients?
机构信息
Department of Surgery, Rijnstate Hospital, Arnhem, The Netherlands.
出版信息
Obes Surg. 2011 Feb;21(2):207-11. doi: 10.1007/s11695-010-0316-7.
BACKGROUND
Recently, the laparoscopic sleeve gastrectomy (LSG) has become popular as a single-stage procedure for the treatment of morbid obesity and its co-morbidities. However, the incidence of micronutrient deficiencies after LSG have hardly been researched.
METHODS
From January 2005 to October 2008, 60 patients underwent LSG. All patients were instructed to take daily vitamin supplements. Patients were tested for micronutrient deficiencies 6 and 12 months after surgery.
RESULTS
Anemia was diagnosed in 14 (26%) patients. Iron, folic acid, and vitamin B12 deficiency was found in 23 (43%), eight (15%), and five (9%) patients, respectively. Vitamin D and albumin deficiency was diagnosed in 21 (39%) and eight (15%) patients. Hypervitaminosis A, B1, and B6 were diagnosed in 26 (48%), 17 (31%), and 13 (30%) patients, respectively.
CONCLUSIONS
Due to inadequate intake and uptake of micronutrients, patients who underwent LSG are at serious risk for developing micronutrient deficiencies. Moreover, some vitamins seem to increase to chronic elevated levels with possible complications in the long-term. Multivitamins and calcium tablets should be regarded only as a minimum and supplements especially for iron, vitamin B12, vitamin D, and calcium should be added to this regimen based on regular blood testing.
背景
最近，腹腔镜袖状胃切除术（LSG）已成为治疗病态肥胖及其合并症的一种单一阶段手术而受到欢迎。然而，LSG 后微量营养素缺乏的发生率几乎没有被研究过。
方法
2005 年 1 月至 2008 年 10 月，60 例患者接受了 LSG。所有患者均被指示每日服用维生素补充剂。术后 6 个月和 12 个月对患者进行微量营养素缺乏检测。
结果
诊断出 14 例（26%）贫血患者。23 例（43%）、8 例（15%）和 5 例（9%）患者分别发现铁、叶酸和维生素 B12 缺乏。21 例（39%）和 8 例（15%）患者诊断出维生素 D 和白蛋白缺乏。26 例（48%）、17 例（31%）和 13 例（30%）患者分别诊断出维生素 A、B1 和 B6 过量。
结论
由于摄入和吸收微量营养素不足，接受 LSG 的患者有严重的发生微量营养素缺乏的风险。此外，一些维生素似乎会在长期内增加到慢性升高水平，可能导致并发症。多种维生素和钙片剂应仅被视为最低限度，应根据定期血液检查，在该方案中添加特别用于铁、维生素 B12、维生素 D 和钙的补充剂。
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