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产后先后发生两种不同的输血反应(输血相关循环超负荷和输血相关急性肺损伤)。

Post-partum sequential occurrence of two diverse transfusion reactions (transfusion associated circulatory overload and transfusion related acute lung injury).

作者信息

Haldar Rudrashish, Samanta Sukhen

机构信息

Department of Anaesthesiology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.

出版信息

J Emerg Trauma Shock. 2013 Oct;6(4):283-6. doi: 10.4103/0974-2700.120378.

DOI:10.4103/0974-2700.120378
PMID:24339663
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3841537/
Abstract

Transfusion associated circulatory overload (TACO) and transfusion related acute lung injury (TRALI) are two dissimilar pathological conditions associated with transfusion of blood products where the time course of the events and clinical presentation overlap leading to uncertainty in establishing the diagnosis and initiating the treatment, which otherwise differs. We encountered a case where a patient of post-partum hemorrhage developed TACO in the immediate post-operative period due to aggressive resuscitative attempts with blood products. The patient's condition was appropriately diagnosed and was managed according to the clinical scenario, and the condition abated. Subsequently, on the third post-operative day the patient again required blood product transfusions following which the patient developed TRALI, the diagnosis of which was also established and adequate treatment strategy was undertaken.

摘要

输血相关循环超负荷(TACO)和输血相关急性肺损伤(TRALI)是与血液制品输注相关的两种不同病理状况,在这些情况中,事件的时间进程和临床表现相互重叠,导致在确立诊断和启动治疗方面存在不确定性,而这两种情况的治疗方法是不同的。我们遇到了这样一个病例,一名产后出血患者在术后即刻因积极输注血液制品进行复苏尝试而发生了TACO。该患者的病情得到了恰当诊断,并根据临床情况进行了处理,病情得到缓解。随后,在术后第三天,该患者再次需要输注血液制品,之后发生了TRALI,其诊断也得以确立,并采取了适当的治疗策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b535/3841537/89e89a0f580e/JETS-6-283-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b535/3841537/99837806db66/JETS-6-283-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b535/3841537/0e8e160ebe62/JETS-6-283-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b535/3841537/89e89a0f580e/JETS-6-283-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b535/3841537/99837806db66/JETS-6-283-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b535/3841537/0e8e160ebe62/JETS-6-283-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b535/3841537/89e89a0f580e/JETS-6-283-g003.jpg

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本文引用的文献

1
Pulmonary transfusion reactions.肺输注反应。
Transfus Med Hemother. 2008 Oct;35(5):337-45. doi: 10.1159/000151349. Epub 2008 Sep 18.
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Transfusion-related acute lung injury: current concepts for the clinician.输血相关急性肺损伤:临床医生的最新概念
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Transfusion-related acute lung injury: definition and review.输血相关急性肺损伤:定义与综述
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Toward an understanding of transfusion-related acute lung injury: statement of a consensus panel.关于理解输血相关急性肺损伤:共识小组声明
Transfusion. 2004 Dec;44(12):1774-89. doi: 10.1111/j.0041-1132.2004.04347.x.
8
Fatalities caused by TRALI.输血相关急性肺损伤导致的死亡
Transfus Med Rev. 2004 Jul;18(3):184-8. doi: 10.1016/j.tmrv.2004.03.004.
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Transfusion and the lung: circulatory overload and acute lung injury.输血与肺:循环超负荷和急性肺损伤。
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The pathogenesis of acute pulmonary edema associated with hypertension.高血压相关急性肺水肿的发病机制。
N Engl J Med. 2001 Jan 4;344(1):17-22. doi: 10.1056/NEJM200101043440103.