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De Vega 瓣环成形术治疗功能性三尖瓣反流:三尖瓣瓣口指数概念可优化三尖瓣环缩小术。

De Vega annuloplasty for functional tricupsid regurgitation: concept of tricuspid valve orifice index to optimize tricuspid valve annular reduction.

机构信息

Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul, Korea.

出版信息

J Korean Med Sci. 2013 Dec;28(12):1756-61. doi: 10.3346/jkms.2013.28.12.1756. Epub 2013 Nov 26.

DOI:10.3346/jkms.2013.28.12.1756
PMID:24339705
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3857371/
Abstract

We evaluated long-term results of De Vega annuloplasty measured by cylindrical sizers for functional tricuspid regurgitation (FTR) and analyzed the impact of measured annular size on the late recurrence of tricuspid valve regurgitation. Between 2001 and 2011, 177 patients (57.9±10.5 yr) underwent De Vega annuloplasty for FTR. Three cylindrical sizers (actual diameters of 29.5, 31.5, and 33.5 mm) were used to reproducibly reduce the tricuspid annulus. Long-term outcomes were evaluated and risk factor analyses for the recurrence of FTR ≥3+ were performed. Measured annular diameter indexed by patient's body surface area was included in the analyses as a possible risk factor. Operative mortality occurred in 8 patients (4.5%). Ten-year overall and cardiac death-free survivals were 80.5% and 90.8%, respectively. Five and 10-yr freedom rates from recurrent FTR were 96.5% and 93.1%, respectively. Cox proportional hazard model revealed that higher indexed annular size was the only risk factor for the recurrence of FTR (P=0.006). A minimal P value approach demonstrated that indexed annular diameter of 22.5 mm/m(2) was a cut-off value predicting the recurrence of FTR. De Vega annuloplasty for FTR results in low rates of recurrent FTR in the long-term. Tricuspid annulus should be reduced appropriately considering patients' body size to prevent recurrent FTR.

摘要

我们评估了 De Vega 瓣环成形术治疗功能性三尖瓣反流(FTR)的长期结果,分析了测量的瓣环大小对三尖瓣反流复发的影响。2001 年至 2011 年间,177 例患者(57.9±10.5 岁)因 FTR 接受了 De Vega 瓣环成形术。使用 3 种圆柱测量器(实际直径分别为 29.5、31.5 和 33.5mm)可重复缩小三尖瓣环。评估长期结果,并对 FTR≥3+复发的危险因素进行分析。将通过患者体表面积索引的测量瓣环直径作为可能的危险因素纳入分析。手术死亡率为 8 例(4.5%)。10 年总生存率和无心脏死亡率分别为 80.5%和 90.8%。5 年和 10 年复发 FTR 的无事件生存率分别为 96.5%和 93.1%。Cox 比例风险模型显示,较高的索引瓣环大小是 FTR 复发的唯一危险因素(P=0.006)。最小 P 值法表明,22.5mm/m2 的索引瓣环直径是预测 FTR 复发的截断值。De Vega 瓣环成形术治疗 FTR 的长期结果复发 FTR 的发生率较低。应根据患者的体型适当缩小三尖瓣环,以防止 FTR 复发。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27b7/3857371/e86d1201ca76/jkms-28-1756-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27b7/3857371/30619a76941e/jkms-28-1756-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27b7/3857371/fe199a6d0314/jkms-28-1756-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27b7/3857371/e86d1201ca76/jkms-28-1756-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27b7/3857371/30619a76941e/jkms-28-1756-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27b7/3857371/fe199a6d0314/jkms-28-1756-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27b7/3857371/e86d1201ca76/jkms-28-1756-g003.jpg

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