Kettunen Olli, Vuorela Marjo, Kuusi Markku, Kantala Tuija, Maunula Leena, Jalava Katri, Blomster Timo, Koskela Ritva, Haapasaari Kirsi-Maria
OYS.
Helsingin yliopisto.
Duodecim. 2013;129(20):2169-73.
We describe the first verified domestic HEV case in a previously healthy 53-year-old man who presented a three-day history of upper stomach pain, nausea, fever, arthralgia and fatigue. At the first phase laboratory tests revealed high levels of AST and ALT and at the second phase high levels of bilirubin. Serum was positive for anti-HEV IgM and for HEV RNA confirming the diagnosis of acute hepatitis E. The HEV was genotype 3. Jaundice resolved in three months. In nonendemic areas autochthonous hepatitis E is more common than previously recognized and is possible in patients with acute hepatitis.
我们描述了首例经证实的国内戊型肝炎病例，患者为一名53岁既往健康男性，出现上腹部疼痛、恶心、发热、关节痛和疲劳等症状三天。第一阶段实验室检查显示谷草转氨酶（AST）和谷丙转氨酶（ALT）水平升高，第二阶段胆红素水平升高。血清抗戊型肝炎病毒免疫球蛋白M（anti-HEV IgM）和戊型肝炎病毒核糖核酸（HEV RNA）呈阳性，确诊为急性戊型肝炎。该戊型肝炎病毒为3型。黄疸在三个月内消退。在非流行地区，散发性戊型肝炎比以前认为的更为常见，急性肝炎患者也有可能感染。
