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小儿活体肝移植中迟发性门静脉并发症的管理

Management of late-onset portal vein complications in pediatric living-donor liver transplantation.

作者信息

Cho Yong-Pil, Kim Kyung-Mo, Ha Tae-Yong, Ko Gi-Young, Hwang Jae-Yeon, Park Hojong, Chung Young Soo, Yoon Taein, Hwang Shin, Jun Heungman, Kwon Tae-Won, Lee Sung-Gyu

机构信息

Division of Vascular Surgery, Department of Surgery, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Korea.

出版信息

Pediatr Transplant. 2014 Feb;18(1):64-71. doi: 10.1111/petr.12204. Epub 2013 Dec 16.

Abstract

The purpose of this study was to evaluate retrospectively the results of PTA for late-onset PV complications after pediatric LDLT and to assess whether a meso-Rex shunt is a viable option for treating restenosis of the PV after PTA in selected cases. Seventy-five children who underwent adult-to-child LDLT were included in this study, and there were six late-onset PV complications (8.0%). The initial therapeutic approach was PTA, with or without stent: PTA with balloon dilation for three children, PTA with stent placement for one child, and failure to cannulate the occluded PV for two children. A meso-Rex shunt was performed in the two children after failed PTA: One suffered complete obstruction of the main PV, and the other, restenosis with total thrombosis after PTA with stent. The PTA was a technical and clinical success in four with PV stenosis of the six patients (66.7%), and successful application of a meso-Rex shunt in the other two children resulted in restoration of PV flow. In conclusion, PTA is a safe and effective procedure for treating late-onset PV stenosis after pediatric LDLT. However, in growing pediatric recipients with restenosis of the PV after PTA or chronic PV thrombosis, a meso-Rex shunt may be a better choice for late-onset PV complications.

摘要

本研究的目的是回顾性评估儿童活体肝移植(LDLT)后迟发性门静脉(PV)并发症的经皮腔内血管成形术(PTA)结果,并评估在特定病例中,肠系膜上静脉-雷克斯分流术是否是治疗PTA后门静脉再狭窄的可行选择。本研究纳入了75例接受成人-儿童LDLT的儿童,其中有6例迟发性PV并发症(8.0%)。初始治疗方法为PTA,有或无支架:3例儿童采用球囊扩张PTA,1例儿童采用支架置入PTA,2例儿童未能成功穿刺闭塞的PV。2例PTA失败的儿童接受了肠系膜上静脉-雷克斯分流术:1例主PV完全阻塞,另1例在支架置入PTA后出现再狭窄并完全血栓形成。6例PV狭窄患者中有4例PTA在技术和临床方面取得成功(66.7%),另外2例儿童成功应用肠系膜上静脉-雷克斯分流术恢复了PV血流。总之,PTA是治疗儿童LDLT后迟发性PV狭窄的一种安全有效的方法。然而,对于PTA后门静脉再狭窄或慢性PV血栓形成的成长中的儿童受者,肠系膜上静脉-雷克斯分流术可能是治疗迟发性PV并发症的更好选择。

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