• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

社区获得性革兰氏阴性菌血症期间的肺部浸润:一项回顾性单中心研究。

Pulmonary infiltrates during community acquired Gram-negative bacteremia: a retrospective single centre study.

机构信息

Department of Intensive Care, Odense University Hospital, Sdr, Boulevard 29, 5000 Odense C, Denmark.

出版信息

Scand J Trauma Resusc Emerg Med. 2013 Dec 17;21:88. doi: 10.1186/1757-7241-21-88.

DOI:10.1186/1757-7241-21-88
PMID:24341830
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3878591/
Abstract

BACKGROUND

The primary aim of this study was to describe the frequency of pulmonary infiltrates on chest X-ray (CXR) during community acquired Gram-negative bacteremia at a single centre in Denmark.

METHODS

The patients were retrospectively identified from the laboratory information system and clinical and radiological data were retrieved from the electronic health records. Overall 114 patients with E.coli or K.pneumoniae bacteremia fulfilled the inclusion criteria during the period 2009-2010.

RESULTS

CXR was performed in 77% of cases (80% of E.coli and 56% of K.pneumoniae) among which infiltrates were identified in 34%. The two most frequent localizations of infiltrates during E.coli bacteremia were lower lobe/basal (56%) and diffuse (22%). Furthermore, 30% of infiltrates were bilateral while 40% were present on the right lung and 30% on the left lung.

CONCLUSIONS

In conclusion, the presence of infiltrates during community acquired Gram-negative bacteremia was very frequent in our population.

摘要

背景

本研究的主要目的是描述在丹麦的一个单一中心,社区获得性革兰氏阴性菌血症患者的胸部 X 线(CXR)上肺部浸润的频率。

方法

从实验室信息系统中回顾性地确定患者,从电子健康记录中检索临床和放射学数据。在 2009-2010 年期间,符合纳入标准的大肠杆菌或肺炎克雷伯菌血症患者共有 114 例。

结果

在 77%的病例中进行了 CXR(大肠杆菌为 80%,肺炎克雷伯菌为 56%),其中 34%发现有浸润。大肠杆菌菌血症中浸润最常见的两个部位是下叶/基底部(56%)和弥漫性(22%)。此外,30%的浸润是双侧的,40%位于右肺,30%位于左肺。

结论

总之,我们的人群中社区获得性革兰氏阴性菌血症患者存在浸润的情况非常普遍。

相似文献

1
Pulmonary infiltrates during community acquired Gram-negative bacteremia: a retrospective single centre study.社区获得性革兰氏阴性菌血症期间的肺部浸润:一项回顾性单中心研究。
Scand J Trauma Resusc Emerg Med. 2013 Dec 17;21:88. doi: 10.1186/1757-7241-21-88.
2
Propensity score matched analysis comparing the clinical outcome of Klebsiella pneumoniae and Escherichia coli causing community-onset monomicrobial bacteremia.倾向评分匹配分析比较肺炎克雷伯菌和大肠埃希菌引起社区获得性单微生物菌血症的临床结局。
Medicine (Baltimore). 2017 Jun;96(26):e7075. doi: 10.1097/MD.0000000000007075.
3
Incidence of community-onset extended-spectrum β-lactamase-producing and infections: an 11-year population-based study in Denmark.社区获得性产超广谱β-内酰胺酶和感染的发生率:丹麦一项为期 11 年的基于人群的研究。
Infect Dis (Lond). 2020 Aug;52(8):547-556. doi: 10.1080/23744235.2020.1763452. Epub 2020 May 13.
4
Community-onset Escherichia coli and Klebsiella pneumoniae bacteremia: influence of health care exposure on antimicrobial susceptibility.社区获得性大肠杆菌和肺炎克雷伯菌血流感染:医疗保健暴露对抗菌药物敏感性的影响
Diagn Microbiol Infect Dis. 2006 Jun;55(2):135-41. doi: 10.1016/j.diagmicrobio.2006.01.004. Epub 2006 Mar 9.
5
Risk factors for 28-day mortality in elderly patients with extended-spectrum β-lactamase (ESBL)-producing Escherichia coli and Klebsiella pneumoniae bacteremia.产超广谱β-内酰胺酶(ESBL)大肠埃希菌和肺炎克雷伯菌血症老年患者 28 天死亡率的危险因素。
Arch Gerontol Geriatr. 2014 Jan-Feb;58(1):105-9. doi: 10.1016/j.archger.2013.07.002. Epub 2013 Aug 8.
6
Laboratory identification, risk factors, and clinical outcomes of patients with bacteremia due to Escherichia coli and Klebsiella pneumoniae producing extended-spectrum and AmpC type β-lactamases.产超广谱和 AmpC 型β-内酰胺酶的大肠埃希菌和肺炎克雷伯菌菌血症患者的实验室鉴定、危险因素和临床结局。
J Microbiol Immunol Infect. 2012 Jun;45(3):193-9. doi: 10.1016/j.jmii.2011.11.003. Epub 2012 May 12.
7
Impact of appropriateness of empiric therapy on outcomes in community-onset bacteremia by extended-spectrum-β-lactamase producing Escherichia coli and Klebisella pneumoniae definitively treated with carbapenems.产超广谱β-内酰胺酶大肠埃希菌和肺炎克雷伯菌社区获得性血流感染经验性治疗适宜性对碳青霉烯类药物确定性治疗结局的影响。
Eur J Clin Microbiol Infect Dis. 2017 Nov;36(11):2093-2100. doi: 10.1007/s10096-017-3031-7. Epub 2017 Jun 23.
8
Risk factors for in-hospital mortality in patients with type 2 diabetes complicated by community-acquired Klebsiella pneumoniae bacteremia.2型糖尿病合并社区获得性肺炎克雷伯菌血症患者院内死亡的危险因素
J Formos Med Assoc. 2015 Oct;114(10):916-22. doi: 10.1016/j.jfma.2015.07.011. Epub 2015 Aug 24.
9
[Hospital and community-acquired β-lactamases-producing Escherichia coli and Klebsiella pneumoniae at hospitals in Hermosillo, Sonora].
Salud Publica Mex. 2011 Jul-Aug;53(4):341-4. doi: 10.1590/s0036-36342011000400009.
10
Clinical characteristics, antimicrobial resistance and capsular types of community-acquired, healthcare-associated, and nosocomial bacteremia.社区获得性、医疗保健相关性和医院获得性菌血症的临床特征、抗菌药物耐药性和荚膜型。
Antimicrob Resist Infect Control. 2019 Jan 3;8:1. doi: 10.1186/s13756-018-0426-x. eCollection 2019.

本文引用的文献

1
Prognostic value of endotoxemia in patients with Gram-negative bacteremia is bacterial species dependent.内毒素血症对革兰氏阴性菌血症患者的预后价值取决于细菌种类。
J Innate Immun. 2013;5(6):555-64. doi: 10.1159/000347172. Epub 2013 Apr 13.
2
TLR4 activation of TRPC6-dependent calcium signaling mediates endotoxin-induced lung vascular permeability and inflammation.TLR4 通过激活 TRPC6 依赖性钙信号转导介导内毒素诱导的肺血管通透性和炎症反应。
J Exp Med. 2012 Oct 22;209(11):1953-68. doi: 10.1084/jem.20111355. Epub 2012 Oct 8.
3
Models and mechanisms of acute lung injury caused by direct insults.直接损伤导致急性肺损伤的模型和机制。
Eur J Cell Biol. 2012 Jun-Jul;91(6-7):590-601. doi: 10.1016/j.ejcb.2011.11.004. Epub 2012 Jan 26.
4
Induction of acute respiratory distress syndrome in rats by lipopolysaccharide and its effect on oxidative stress and antioxidant status in lung.脂多糖诱导大鼠急性呼吸窘迫综合征及其对肺组织氧化应激和抗氧化状态的影响
Indian J Biochem Biophys. 2010 Oct;47(5):278-84.
5
The value of the lipopolysaccharide-induced acute lung injury model in respiratory medicine.脂多糖诱导的急性肺损伤模型在呼吸医学中的价值。
Expert Rev Respir Med. 2010 Dec;4(6):773-83. doi: 10.1586/ers.10.71.
6
Flagellin from gram-negative bacteria is a potent mediator of acute pulmonary inflammation in sepsis.革兰氏阴性菌的鞭毛蛋白是脓毒症中急性肺部炎症的强效介质。
Shock. 2003 Feb;19(2):131-7. doi: 10.1097/00024382-200302000-00008.
7
Antibiotic therapy and outcome of monomicrobial gram-negative bacteraemia: a 3-year population-based study.
Scand J Infect Dis. 1997;29(6):601-6. doi: 10.3109/00365549709035903.
8
The acute respiratory distress syndrome.
N Engl J Med. 1995 Jan 5;332(1):27-37. doi: 10.1056/NEJM199501053320106.
9
Endotoxin and lung injury.内毒素与肺损伤。
Am Rev Respir Dis. 1986 May;133(5):913-27.
10
Endotoxaemia: an early predictor of septicaemia in febrile patients.内毒素血症:发热患者败血症的早期预测指标。
Lancet. 1988 Mar 19;1(8586):605-9. doi: 10.1016/s0140-6736(88)91412-2.