Department of Social Medicine, School of Public Health, Central South University, Changsha, China; Mental Health Institute, Second Xiangya Hospital, Central South University, Changsha, China.
Department of Social Medicine, School of Public Health, Central South University, Changsha, China.
Addict Behav. 2014 Mar;39(3):573-9. doi: 10.1016/j.addbeh.2013.11.003. Epub 2013 Nov 10.
Little is known about gender difference in correlates of antisocial personality disorder (ASPD) among drug users.
To detect gender difference in correlates of ASPD in a Chinese heroin dependent sample.
Structured interviews were conducted among 882 heroin dependent users in two compulsory isolation settings in Changsha, China. Descriptive statistics were employed to report sample characteristics by gender. Bivariate relationships were examined between co-occurring ASPD and variables measuring demographic, drug use, and psychiatric co-morbidities. Multivariate logistic regressions with stepwise forward method were conducted to determine independent predictors for co-occurring ASPD. All analyses examining correlates of co-occurring ASPD were conducted for the total, the male and the female participants respectively to detect both the common and the unique correlates of ASPD by gender.
Of the total participants, 41.4% (54.2% of males and 15.4% of females) met the DSM-IV criteria of ASPD. For male participants, lower educational level, unemployment, unmarried, younger age at first heroin use, previous history of compulsory treatment, larger amounts of heroin used per day and poly-drug abuse during past month before admission, as well as psychiatric co-morbidities of lifetime major depressive disorder and borderline personality disorder were independent predictors for co-occurring ASPD; while for female participants, only three variables: younger age at first heroin use, paranoid personality disorder and borderline personality disorder were independent predictors for co-occurring ASPD.
Gender differences in prevalence and correlates of ASPD among heroin dependent users were detected. The findings highlight a need for gender-specific interventions.
关于吸毒者反社会人格障碍（ASPD）相关因素的性别差异知之甚少。
在中国海洛因依赖者样本中发现与 ASPD 相关的性别差异。
在中国长沙的两个强制隔离场所，对 882 名海洛因依赖者进行了结构式访谈。按性别报告样本特征的描述性统计。在共病 ASPD 与衡量人口统计学、药物使用和精神共病的变量之间，检查了双变量关系。采用逐步向前法的多元逻辑回归，确定共病 ASPD 的独立预测因子。分别对总样本、男性和女性参与者进行了共病 ASPD 相关因素的分析，以检测性别共有的和特有的 ASPD 相关因素。
在所有参与者中，41.4%（男性为 54.2%，女性为 15.4%）符合 DSM-IV 中 ASPD 的标准。对于男性参与者，较低的教育水平、失业、未婚、首次使用海洛因的年龄较小、之前有过强制治疗史、每天使用的海洛因量较大以及在入院前一个月内同时滥用多种药物，以及终生重性抑郁障碍和边缘型人格障碍的精神共病是共病 ASPD 的独立预测因子；而对于女性参与者，只有三个变量：首次使用海洛因的年龄较小、偏执型人格障碍和边缘型人格障碍是共病 ASPD 的独立预测因子。
在海洛因依赖者中，ASPD 的患病率和相关因素存在性别差异。这些发现强调了需要针对性别进行干预。
