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[巴西老年人健康与生活方式研究中的医学评估与测量]

[Medical assessments and measurements in ELSA-Brasil].

作者信息

Mill Jose Geraldo, Pinto Karina, Griep Rosane Härter, Goulart Alessandra, Foppa Murilo, Lotufo Paulo A, Maestri Marcelo K, Ribeiro Antonio Luiz, Andreão Rodrigo Varejão, Dantas Eduardo Miranda, Oliveira Ilka, Fuchs Sandra C, Cunha Roberto de Sá, Bensenor Isabela M

出版信息

Rev Saude Publica. 2013 Jun;47 Suppl 2:54-62. doi: 10.1590/s0034-8910.2013047003851.

Abstract

The article describes assessments and measurements performed in the Brazilian Longitudinal Study for Adult Health (ELSA-Brasil). Some assessments including anthropometric assessment, casual blood pressure measurement, and ankle-brachial index have an established clinical application while others including pulse wave velocity, heart rate variability, and carotid intima-media thickness have no established application and do not have reference values for healthy Brazilian population but may be important predictors of cardiovascular outcomes. Blood pressure measurement following postural change maneuver was included in the ELSA-Brasil because it has not been much tested in epidemiological studies. Innovative approaches were developed for assessing the ankle-brachial index using an automatic device instead of the mercury column to measure blood pressure and for assessing the anterior-posterior diameter of the right lobe of the liver by ultrasound for quantitative assessment of nonalcoholic fatty liver disease. All ELSA-Brasil subjects were younger (35 years or more) than those included in other cohorts studying subclinical atherosclerosis. The inclusion of younger individuals and a variety of assessments make the ELSA-Brasil a relevant epidemiology study nationwide and worldwide.

摘要

这篇文章描述了在巴西成人健康纵向研究(ELSA - Brasil)中所进行的评估和测量。一些评估,包括人体测量评估、随机血压测量和踝臂指数,已有既定的临床应用,而其他一些评估,包括脉搏波速度、心率变异性和颈动脉内膜中层厚度,尚无既定应用,且没有针对巴西健康人群的参考值,但可能是心血管疾病结局的重要预测指标。体位改变动作后的血压测量被纳入ELSA - Brasil,因为其在流行病学研究中尚未得到充分测试。开发了创新方法,使用自动设备而非汞柱来测量血压以评估踝臂指数,以及通过超声评估肝脏右叶的前后径以对非酒精性脂肪性肝病进行定量评估。所有ELSA - Brasil的受试者都比其他研究亚临床动脉粥样硬化的队列中的受试者更年轻(35岁及以上)。纳入更年轻的个体以及进行多种评估,使得ELSA - Brasil成为一项在巴西全国乃至全球都具有相关性的流行病学研究。

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