Division of Applied Life Science (BK21plus/WCU Program), Graduate School of Gyeongsang National University, Plant Molecular Biology & Biotechnology Research Center (PMBBRC), Jinju 660-701, Korea.
J Exp Bot. 2014 Apr;65(7):1737-49. doi: 10.1093/jxb/ert422. Epub 2013 Dec 17.
Plant cells utilize mobile transcription factors to transmit intercellular signals when they perceive environmental stimuli or initiate developmental programmes. Studies on these novel cell-to-cell signals have accumulated multiple pieces of evidence showing that non-cell-autonomous transcription factors play pivotal roles in most processes related to the formation and development of plant organs. Recent studies have explored the evolution of mobile transcription factors and proposed mechanisms for their trafficking through plasmodesmata, where a selective system exists to facilitate this process. Mobile transcription factors contribute to the diversity of the intercellular signalling network, which is also established by peptides, hormones, and RNAs. Crosstalk between mobile transcription factors and other intercellular molecules leads to the development of complex biological signalling networks in plants. The regulation of plasmodesmata appears to have been another major step in controlling the intercellular trafficking of transcription factors based on studies of many plasmodesmal components. Furthermore, diverse omics approaches are being successfully applied to explore a large number of candidate transcription factors as mobile signals in plants. Here, we review these fascinating discoveries to integrate current knowledge of non-cell-autonomous transcription factors.
植物细胞在感知环境刺激或启动发育程序时，会利用可移动的转录因子来传递细胞间信号。对这些新型细胞间信号的研究积累了大量证据，表明非细胞自主转录因子在与植物器官形成和发育相关的大多数过程中发挥着关键作用。最近的研究探讨了可移动转录因子的进化，并提出了它们通过胞间连丝运输的机制，其中存在一个选择性系统来促进这个过程。可移动转录因子为细胞间信号网络的多样性做出了贡献，该网络还由肽、激素和 RNA 建立。可移动转录因子与其他细胞间分子之间的相互作用导致植物中复杂的生物信号网络的发展。基于对许多胞间连丝成分的研究，胞间连丝的调节似乎是控制转录因子细胞间运输的另一个主要步骤。此外，多样化的组学方法正在成功地应用于探索大量候选转录因子作为植物中的可移动信号。在这里，我们回顾这些引人入胜的发现，以整合非细胞自主转录因子的现有知识。
