吡仑帕奈：一种用于治疗癫痫的选择性 AMPA 拮抗剂。
Perampanel: a selective AMPA antagonist for treating seizures.
机构信息
Department of Neurology, Johns Hopkins School of Medicine, Baltimore, MD.
出版信息
Epilepsy Curr. 2013 Nov;13(6):269-72. doi: 10.5698/1535-7597-13.6.269.
Abstract
Perampanel is a selective, noncompetitive AMPA receptor antagonist that has recently been approved for treating localization-related epilepsy. This article reviews the pharmacology, clinical development, efficacy, and safety/tolerability of perampanel.
摘要
吡仑帕奈是一种选择性、非竞争性 AMPA 受体拮抗剂，最近已被批准用于治疗与定位相关的癫痫。本文综述了吡仑帕奈的药理学、临床开发、疗效和安全性/耐受性。
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