轻度认知障碍老年人的认知活动和日常生活工具性活动
Cognitive activities and instrumental activity of daily living in older adults with mild cognitive impairment.
作者信息
Doi Takehiko, Shimada Hiroyuki, Makizako Hyuma, Lee Sangyoon, Park Hyuntae, Tsutsumimoto Kota, Uemura Kazuki, Yoshida Daisuke, Anan Yuya, Suzuki Takao
机构信息
Section for Health Promotion, Department for Research and Development to Support Independent Life of Elderly, Obu, Japan ; Research Institute, National Center for Geriatrics and Gerontology, Obu, Japan ; Japan Society for the Promotion of Science, Tokyo, Japan.
Section for Health Promotion, Department for Research and Development to Support Independent Life of Elderly, Obu, Japan.
出版信息
Dement Geriatr Cogn Dis Extra. 2013 Oct 26;3(1):398-406. doi: 10.1159/000355553. eCollection 2013.
AIMS
This study aimed to identify differences in the implementation of cognitive activities and instrumental activities of daily living (IADLs) between healthy individuals and subjects with mild cognitive impairment (MCI).
METHODS
The study included 2,498 cognitively healthy subjects (mean age, 71.2 ± 5.1 years) and 809 MCI subjects (mean age, 71.8 ± 5.4 years). The subjects were interviewed regarding their participation in cognitive activities and the implementation of IADLs.
RESULTS
We found a significant association between participation in any cognitive activities (p < 0.001), using a bus or a train (p < 0.001), and MCI. After adjusting for covariates, cognitive activity of any type remained significantly associated with MCI (p < 0.005) but not with the implementation of IADLs.
CONCLUSIONS
Our study revealed that greater participation in cognitive activity was associated with lower odds of MCI. Participation in cognitive activities may reflect differences between healthy and MCI subjects. To clarify the causal relationship between cognitive activities and MCI, further studies are required.
目的
本研究旨在确定健康个体与轻度认知障碍（MCI）患者在认知活动和日常生活工具性活动（IADL）实施方面的差异。
方法
该研究纳入了2498名认知健康受试者（平均年龄71.2±5.1岁）和809名MCI受试者（平均年龄71.8±5.4岁）。就受试者参与认知活动和IADL的实施情况对其进行了访谈。
结果
我们发现参与任何认知活动（p<0.001）、乘坐公交车或火车（p<0.001）与MCI之间存在显著关联。在对协变量进行调整后，任何类型的认知活动仍与MCI显著相关（p<0.005），但与IADL的实施情况无关。
结论
我们的研究表明，更多地参与认知活动与MCI几率较低相关。参与认知活动可能反映了健康受试者与MCI受试者之间的差异。为阐明认知活动与MCI之间的因果关系，需要进一步研究。
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