Mui Wing Ho, Lee Ka Chai, Chiu Sin Chuen, Pang Chun Yin, Chu Sau Kwan, Man Chi Wai, Wong Chi Sing, Sze Wing Kin, Tung Yuk
Department of Clinical Oncology, Tuen Mun Hospital, Tuen Mun, Hong Kong SAR, P.R. China.
Department of Pathology, Tuen Mun Hospital, Tuen Mun, Hong Kong SAR, P.R. China.
Oncol Lett. 2014 Jan;7(1):199-202. doi: 10.3892/ol.2013.1670. Epub 2013 Nov 8.
We present a case of rare primary yolk sac tumour of the urinary bladder in adulthood. A 31-year-old female patient presented with a history of chronic ketamine abuse, which has not previously been shown to be associated with malignancy development. The final diagnosis was established only after radical cystectomy. A computed tomography (CT) scan showed paraaortic lymph node metastasis. The patient was treated with systemic chemotherapy. A review of the literature revealed that surgical excision and cisplatin-based chemotherapy remain to be the standard of care for extragonadal yolk sac tumours.
我们报告一例成年期罕见的原发性膀胱卵黄囊瘤病例。一名31岁女性患者有长期滥用氯胺酮的病史,此前未发现其与恶性肿瘤发生有关。最终诊断仅在根治性膀胱切除术后得以确立。计算机断层扫描(CT)显示腹主动脉旁淋巴结转移。该患者接受了全身化疗。文献回顾显示,手术切除和顺铂为基础的化疗仍然是性腺外卵黄囊瘤的标准治疗方法。