Petrova T R, Skibitskiĭ V V
Ter Arkh. 1986;58(11):97-101.
A total of 136 patients with paroxysmal supraventricular tachyarrhythmia and tachyform of atrial fibrillation and polytopic extrasystoles were examined. The combination of cardiovascular and psychovegetative disturbances closely related to the expression of psychopathological shifts was revealed. The antiarrhythmic activity of psychotropic drugs (phenibut, sulpiride, pipofezin, tofizopam and falilepsin) depending on the nature of the time course of the emotional-personality status in prolonged intermittent treatment of patients with arrhythmias of the functional and mixed genesis was shown. A negative inotropic effect of phenibut, a hyperdynamic effect of sulpiride, pipofezin, falilepsin and a modulating effect of tofizopam were revealed. Prolonged therapy with psychopharmacological drugs in short courses was proposed.
共检查了136例阵发性室上性心律失常、房颤心动过速型和多源性早搏患者。发现心血管和精神植物神经紊乱的组合与精神病理变化的表现密切相关。显示了精神药物（苯丁胺、舒必利、匹泮氮平、托非索泮和法立普辛）在对功能性和混合性病因的心律失常患者进行长期间歇性治疗时，其抗心律失常活性取决于情绪-人格状态的时间进程性质。揭示了苯丁胺的负性肌力作用、舒必利、匹泮氮平、法立普辛的高动力作用以及托非索泮的调节作用。建议短疗程使用精神药物进行长期治疗。
