Skibitskiĭ V V, Kanorskiĭ S G
Eksp Klin Farmakol. 1993 Sep-Oct;56(5):23-7.
The new Russian drugs gidazepam, a tranquilizer, and befol, an antidepressant, show not only their psychotropic action, but change cardiac electrophysiological function and produce antiarrhythmic effects, which allows them to be used in the treatment of various cardiac arrhythmias. The antiarrhythmic effect of the psychopharmacological agents is largely shown in patients with ventricular premature contraction and paroxysmal tachycardias in the presence of neurocirculatory dystonia, as well as with great deviations of the electrophysiological properties of the cardiac conduction system from the their mean values, by promoting their normalization. The antiarrhythmic effect of gidazepam is higher than that of befol in both patients with neurocirculatory dystonia and those with coronary heart disease.
俄罗斯的新型药物安定epam（一种镇静剂）和贝福ol（一种抗抑郁药）不仅具有精神otropic作用，还能改变心脏电生理功能并产生抗心律失常作用，这使得它们可用于治疗各种心律失常。这些精神药物的抗心律失常作用在神经循环性肌张力障碍患者中，以及心脏传导系统电生理特性与平均值有很大偏差的情况下，主要体现在室性早搏和阵发性心动过速患者身上，通过促进其正常化来实现。在神经循环性肌张力障碍患者和冠心病患者中，安定epam的抗心律失常作用均高于贝福ol。
