首次躁狂发作与使用人绒毛膜促性腺激素治疗肥胖相关：病例报告。
First manic episode associated with use of human chorionic gonadotropin for obesity: a case report.
机构信息
Department of Psychiatry and Behavioral Sciences, Harris County Psychiatric Center, The University of Texas Health Science Center at Houston, Houston, TX, USA; University of Texas Center of Excellence on Mood Disorders, Houston, TX, USA.
出版信息
Bipolar Disord. 2014 Mar;16(2):204-7. doi: 10.1111/bdi.12167. Epub 2013 Dec 18.
BACKGROUND
Although highly controversial, the treatment of obesity with exogenous human chorionic gonadotropin (HCG) remains popular in the USA. We report the case of a patient whose first manic episode was associated with the use of HCG for weight loss.
CASE REPORT
A 32-year-old female patient was admitted to our psychiatric inpatient unit due to a two-week history of manic symptoms. She had no previous history of manic or hypomanic episodes and had completed a 45-day course of sublingual HCG for weight loss immediately prior to the onset of the manic episode. The patient was treated with lithium carbonate and aripiprazole, and progressed with improvement in the symptoms.
CONCLUSION
While it is not possible to definitively link the HCG use to the development of mania, available evidence suggests that HCG may have a contributing role in triggering manic symptomatology.
背景
尽管存在很大争议，但使用外源性人绒毛膜促性腺激素（HCG）治疗肥胖症在美国仍然很流行。我们报告了一例患者的病例，其首次躁狂发作与使用 HCG 减肥有关。
病例报告
一名 32 岁女性患者因两周的躁狂症状被收入我院精神科住院部。她以前没有躁狂或轻躁狂发作的病史，在躁狂发作前刚刚完成了为期 45 天的舌下 HCG 减肥疗程。该患者接受了碳酸锂和阿立哌唑治疗，症状有所改善。
结论
虽然不能确定将 HCG 的使用与躁狂症的发展直接联系起来，但现有证据表明 HCG 可能在引发躁狂症状方面起到一定作用。
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