[短期应激暴露适应对实验性心肌梗死心脏颤动阈值和异位活动的影响]

[Effect of adaptation to short-term stress exposure on the fibrillation threshold and ectopic activity of the heart in experimental myocardial infarct].

作者信息

Diusenov S S

出版信息

Biull Eksp Biol Med. 1987 Mar;103(3):271-3.

Abstract

Preliminary adaptation to short-term stress was shown to prevent the decrease in the heart fibrillation threshold and an increase in ectopic activity which is usually observed in experimental myocardial infarction. This protective effect involves an enhanced activity of the antioxidant system. Therefore, a synthetic antioxidant ionol was applied to prevent disturbances of the heart electrical stability in infarction. It was established that ionol completely prevents the decrease in the electrical threshold and the increase in ectopic activity of the heart in experimental infarction. Thus, it can be concluded that ionol possesses an antiarrhythmic effect.

摘要

初步研究表明，对短期应激的适应性可防止实验性心肌梗死中通常出现的房颤阈值降低和异位活动增加。这种保护作用涉及抗氧化系统活性的增强。因此，应用合成抗氧化剂羟苯二氢吡喃来预防梗死时心脏电稳定性的紊乱。研究发现，羟苯二氢吡喃能完全防止实验性梗死中心脏电阈值的降低和异位活动的增加。因此，可以得出结论，羟苯二氢吡喃具有抗心律失常作用。

相似文献

1

[Effect of adaptation to short-term stress exposure on the fibrillation threshold and ectopic activity of the heart in experimental myocardial infarct].[短期应激暴露适应对实验性心肌梗死心脏颤动阈值和异位活动的影响]

Biull Eksp Biol Med. 1987 Mar;103(3):271-3.

2

[Prevention of a disorder in the electrical stability of the heart in experimental myocardial infarct by using preliminary adaptation to brief stress exposures and the antioxidant ionol].通过对短暂应激暴露进行预先适应和使用抗氧化剂维生素E预防实验性心肌梗死中心脏电稳定性紊乱

Kardiologiia. 1986 Aug;26(8):19-24.

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Adaptation to short-term stress prevents post-infarction hyperactivation of the endothelium and decrease in blood pressure in rats.适应短期应激可预防大鼠心肌梗死后内皮细胞过度激活及血压降低。

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10

[Prevention of ischemic and re-oxygenation arrhythmias and heart fibrillation using the antioxidant ionol].[使用抗氧化剂维生素E防止缺血及再给氧引起的心律失常和心房纤颤]

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