精神分裂症门诊患者的心理社会康复训练：一项随机、心理社会康复训练与单一药物对照研究。
Psychosocial Rehabilitation Training in the Treatment of Schizophrenia Outpatients: A Randomized, Psychosocial Rehabilitation training-and Monomedication-Controlled Study.
机构信息
Ling Wang, Researcher, Research and Education Department, Chongqing Mental Health Center, China.
Jianchu Zhou, Professor, Chief Researcher, Research and Education Department, Chongqing Mental Health Center, China.
出版信息
Pak J Med Sci. 2013 Apr;29(2):597-600. doi: 10.12669/pjms.292.2951.
OBJECTIVE
This study was designed to evaluate the efficacy of psychosocial rehabilitation intervention on schizophrenia.
METHODOLOGY
One hundred forty schizophrenia outpatients in remission stage were randomized to either an antipsychotic monomedication (control group) or an antipsychotic monomedication plus a psychosocial rehabitation training (trial group). Positive and Negative syndrome Scale (PANSS), Disability Screening Schedule (SDSS) were performed longitudinally from baseline to month 18 to evaluate the efficacy.
RESULTS
Significant difference in relapse rate between the control group (42.9%) and the trial group (18.6%) was found at month 18. In patients who didn't relapse, the trial group showed significantly lower PANSS and SDSS score (P<0.05) than did the control group after treatment.
CONCLUSION
Psychosocial rehabilitation intervention could produce a better outcome in terms of reducing relapse and improving the social functioning in schizophrenia.
目的
本研究旨在评估心理社会康复干预对精神分裂症的疗效。
方法
将 140 例缓解期精神分裂症门诊患者随机分为抗精神病药物单一治疗（对照组）或抗精神病药物单一治疗联合心理社会康复训练（试验组）。采用阳性和阴性症状量表（PANSS）、残疾筛查量表（SDSS）从基线到第 18 个月进行纵向评估，以评估疗效。
结果
第 18 个月时，对照组（42.9%）和试验组（18.6%）的复发率差异有统计学意义。在未复发的患者中，治疗后试验组的 PANSS 和 SDSS 评分明显低于对照组（P<0.05）。
结论
心理社会康复干预可降低精神分裂症的复发率，改善社会功能，从而获得更好的疗效。
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