Hajieh Shahbazian, Professor, Endocrinologist, Diabetes Research Center , Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Leila Yazdanpanah, MD, Diabetes Research Center , Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Pak J Med Sci. 2013 May;29(3):730-4. doi: 10.12669/pjms.293.3473.
The aim was assessment of diabetic foot ulcer risk factors according to International Working Group on the Diabetic Foot (IWGDF) consensus.
All referred patients with diabetes were divided into four groups based on IWGDF criteria (without neuropathy, with neuropathy, neuropathy with deformity or vascular disorders, foot ulcer or amputation history).
Mean age of patients was 53.8±10.7 years. Two hundred and sixty nine patients (62/6%) were female and 161(37/4%) were male. Twenty three percent had disturbed sense of vibration, 26% had decreased sensitivity to monofilaments and 17% had decreased pain sensation. Ankle brachial index (ABI) was abnormal in 6%. About 7% had history of prior ulcer. Patients were classified into four risk groups according to IWGDF criteria. Two hundred and seventy seven patients (65%) were in group 0, 75(17%) in group 1, 47 (11%) in group 2 and 31 (7%) in group 3. Patients in higher-risk groups had higher age, longer diabetes duration, higher HbA1C and less training (p=0.0001, 0.001, 0.0001, 0.021 respectively). The risk was higher in the presence of retinopathy (p=0.005). Patient's sex, BMI, smoking and nephropathy did not have significant correlation with risk of diabetic foot ulcer.
This study showed that increase of age, duration of diabetes and HbA1c, lack of training and presence of retinopathy increases the risk of diabetic foot ulcers.
根据国际糖尿病足工作组(IWGDF)的共识,评估糖尿病足溃疡的危险因素。
根据 IWGDF 标准,将所有转诊的糖尿病患者分为四组(无神经病变、有神经病变、有神经病变合并畸形或血管病变、有溃疡或截肢病史)。
患者的平均年龄为 53.8±10.7 岁。269 名患者(62/6%)为女性,161 名(37/4%)为男性。23%的患者振动感觉受损,26%的患者触觉丝感觉减退,17%的患者痛觉减退。踝肱指数(ABI)异常者占 6%。约 7%有既往溃疡史。根据 IWGDF 标准,患者被分为四个危险组。277 名患者(65%)为 0 组,75 名(17%)为 1 组,47 名(11%)为 2 组,31 名(7%)为 3 组。高危组患者年龄较大,糖尿病病程较长,HbA1C 较高,训练较少(p=0.0001,0.001,0.0001,0.021)。存在视网膜病变时风险更高(p=0.005)。患者的性别、BMI、吸烟和肾病与糖尿病足溃疡的风险无显著相关性。
本研究表明,年龄、糖尿病病程和 HbA1c 的增加、缺乏训练和视网膜病变的存在增加了糖尿病足溃疡的风险。