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直觉。

Gut instinct.

作者信息

Bion Julian

出版信息

Crit Care. 2013 Dec 19;17(6):1025. doi: 10.1186/cc13165.

DOI:10.1186/cc13165
PMID:24355080
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4056531/
Abstract

Barriers to the use of selective digestive decontamination include concerns about emergence of resistant organisms, over-estimation of current performance in preventing ventilator-associated pneumonia (VAP), alternative methods of preventing VAP, and misunderstanding of mechanisms of action. A definitive cluster-randomised trial should be undertaken that incorporates practitioner concerns and effect-size preferences.

摘要

选择性消化道去污使用的障碍包括对抗药微生物出现的担忧、对当前预防呼吸机相关性肺炎（VAP）效果的高估、预防VAP的替代方法以及对作用机制的误解。应该进行一项纳入从业者担忧和效应量偏好的确定性整群随机试验。

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1
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2
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Clinical stakeholders' opinions on the use of selective decontamination of the digestive tract in critically ill patients in intensive care units: an international Delphi study.临床利益相关者对重症监护病房危重症患者使用消化道选择性去污的意见：一项国际德尔菲研究。
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本文引用的文献

1
Clinical stakeholders' opinions on the use of selective decontamination of the digestive tract in critically ill patients in intensive care units: an international Delphi study.临床利益相关者对重症监护病房危重症患者使用消化道选择性去污的意见：一项国际德尔菲研究。
Crit Care. 2013 Nov 8;17(6):R266. doi: 10.1186/cc13096.
2
Selective decontamination of the oropharynx and the digestive tract, and antimicrobial resistance: a 4 year ecological study in 38 intensive care units in the Netherlands.口咽部和消化道的选择性去污与抗菌药物耐药性：荷兰38个重症监护病房的4年生态学研究
J Antimicrob Chemother. 2014 Mar;69(3):797-804. doi: 10.1093/jac/dkt416. Epub 2013 Oct 21.
3
Explaining Matching Michigan: an ethnographic study of a patient safety program.解释密歇根匹配法：一项患者安全计划的民族志研究。
Implement Sci. 2013 Jun 20;8:70. doi: 10.1186/1748-5908-8-70.
4
Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock, 2012.拯救脓毒症运动：严重脓毒症和脓毒性休克管理国际指南，2012 年。
Intensive Care Med. 2013 Feb;39(2):165-228. doi: 10.1007/s00134-012-2769-8. Epub 2013 Jan 30.
5
Effect of selective decontamination on antimicrobial resistance in intensive care units: a systematic review and meta-analysis.选择性去污染对重症监护病房抗菌耐药性的影响：系统评价和荟萃分析。
Lancet Infect Dis. 2013 Apr;13(4):328-41. doi: 10.1016/S1473-3099(12)70322-5. Epub 2013 Jan 25.
6
The gut is the epicentre of antibiotic resistance.肠道是抗生素耐药性的中心。
Antimicrob Resist Infect Control. 2012 Nov 27;1(1):39. doi: 10.1186/2047-2994-1-39.
7
Selective decontamination of the digestive tract: the mechanism of action is control of gut overgrowth.选择性消化道去污：作用机制是控制肠道过度生长。
Intensive Care Med. 2012 Nov;38(11):1738-50. doi: 10.1007/s00134-012-2690-1. Epub 2012 Sep 22.
8
'Matching Michigan': a 2-year stepped interventional programme to minimise central venous catheter-blood stream infections in intensive care units in England.“匹配密歇根州”：一项为期两年的阶梯式干预计划，旨在将英格兰重症监护病房的中心静脉导管相关血流感染降至最低。
BMJ Qual Saf. 2013 Feb;22(2):110-23. doi: 10.1136/bmjqs-2012-001325. Epub 2012 Sep 20.
9
What counts? An ethnographic study of infection data reported to a patient safety program.关注什么？向患者安全计划报告的感染数据的民族志研究。
Milbank Q. 2012 Sep;90(3):548-91. doi: 10.1111/j.1468-0009.2012.00674.x.
10
Long-term use of selective decontamination of the digestive tract does not increase antibiotic resistance: a 5-year prospective cohort study.长期使用选择性消化道去污染不会增加抗生素耐药性：一项为期 5 年的前瞻性队列研究。
Intensive Care Med. 2011 Sep;37(9):1458-65. doi: 10.1007/s00134-011-2307-0. Epub 2011 Jul 19.