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基于家庭的吸烟预防计划对吸烟起始的长期影响:一项整群随机对照试验。

Long-term effects of a home-based smoking prevention program on smoking initiation: a cluster randomized controlled trial.

机构信息

Behavioural Science Institute, Radboud University Nijmegen, P.O. Box 9104, 6500 HE Nijmegen, The Netherlands.

Behavioural Science Institute, Radboud University Nijmegen, P.O. Box 9104, 6500 HE Nijmegen, The Netherlands.

出版信息

Prev Med. 2014 Mar;60:65-70. doi: 10.1016/j.ypmed.2013.12.012. Epub 2013 Dec 16.

DOI:10.1016/j.ypmed.2013.12.012
PMID:24355576
Abstract

OBJECTIVE

The aims of the study were to evaluate the long-term effects of a home-based smoking prevention program 'Smoke-free Kids' during preadolescence on smoking initiation during adolescence and to test the potential moderating role of parental smoking, socioeconomic status, and asthma.

METHOD

In 2008, 1478 9-11year old children and their mothers were recruited from 418 elementary schools in the Netherlands. An independent statistician randomly allocated schools to one of the two conditions using a 1:1 ratio (single blind): 728 children in the intervention and 750 in the control condition. The intervention condition received five activity modules, including a communication sheet for mothers, by mail at four-week intervals and one booster module one year after baseline. The control condition received a fact-based intervention only. Intention-to-treat analysis was performed on 1398 non-smoking children at baseline.

RESULTS

In the intervention 10.8% of the children started smoking compared to 12% in the control condition. This difference was non-significant (odds ratio=0.90, 95% confidence interval=0.63-1.27). No moderating effects were found.

CONCLUSION

No effects on smoking initiation after 36months were found. Perhaps, the program was implemented with children that were too young. Programs closer to the age of smoking onset should be tested.

摘要

目的

本研究旨在评估一项基于家庭的青少年前吸烟预防计划“无烟儿童”对青少年吸烟起始的长期影响,并检验父母吸烟、社会经济地位和哮喘的潜在调节作用。

方法

2008 年,从荷兰 418 所小学招募了 1478 名 9-11 岁儿童及其母亲。一名独立的统计学家使用 1:1 的比例(单盲)随机将学校分配到两种条件之一:728 名儿童在干预组,750 名儿童在对照组。干预组通过邮件每四周接收五个活动模块,包括一张给母亲的沟通表,一年后进行一次强化模块。对照组仅接受基于事实的干预。对基线时 1398 名不吸烟的儿童进行意向治疗分析。

结果

干预组有 10.8%的儿童开始吸烟,而对照组有 12%的儿童开始吸烟。差异无统计学意义(优势比=0.90,95%置信区间=0.63-1.27)。未发现调节作用。

结论

36 个月后未发现吸烟起始的影响。也许,该计划是针对年龄较小的儿童实施的。应该测试更接近吸烟起始年龄的项目。

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