Asensio Angel
Servicio de Medicina Preventiva, Hospital Universitario Puerta de Hierro-Majadahonda, Majadahonda, Madrid, España.
Enferm Infecc Microbiol Clin. 2014 Jan;32(1):48-53. doi: 10.1016/j.eimc.2013.11.003. Epub 2013 Dec 17.
Surgical site infections (SSI) are very common, and represent more than 20% of all hospital-acquired infections. SSIs are associated with a higher mortality, as well as to an extended hospital stay and costs, depending on the surgical procedure and type of SSI. Advances in control practices for these infections include improvement in operating room ventilation, sterilization methods, barriers, and surgical techniques, as well as in surgical antimicrobial prophylaxis. For the latter, the antimicrobial agent should: be active against the most common pathogens, be administered in an appropriate dosage and in a time frame to ensure serum and tissue concentrations over the period of potential contamination, be safe, and be administered over the shortest effective time period to minimize adverse events, development of resistances, and cost.
手术部位感染（SSI）非常常见，占所有医院获得性感染的20%以上。根据手术程序和SSI类型，SSIs与更高的死亡率、更长的住院时间和费用相关。这些感染控制措施的进展包括手术室通风、灭菌方法、屏障和手术技术的改进，以及手术抗菌预防的改进。对于后者，抗菌剂应：对最常见的病原体具有活性，以适当的剂量和时间框架给药，以确保在潜在污染期间的血清和组织浓度，安全，并在最短的有效时间内给药，以尽量减少不良事件、耐药性的产生和成本。
