Lebel S, Raymond Y
Exp Cell Res. 1987 Apr;169(2):560-5. doi: 10.1016/0014-4827(87)90216-3.
Peripheral lamina were isolated from rat liver nuclei and probed with a monoclonal antibody reactive against a common domain of all intermediate filament (IF) proteins. The antibody reacted against lamins A and C as expected from their known sequence homology with IF proteins. Lamin B was also recognized by the antibody. These results indicate that lamin B, despite important biochemical differences vs lamins A and C, also shares sequence homology with IF proteins.
从大鼠肝细胞核中分离出外周板层，并用一种针对所有中间丝（IF）蛋白共同结构域的单克隆抗体进行检测。正如从它们与IF蛋白已知的序列同源性所预期的那样，该抗体与核纤层蛋白A和C发生反应。核纤层蛋白B也被该抗体识别。这些结果表明，尽管核纤层蛋白B与核纤层蛋白A和C在重要的生化特性上存在差异，但它也与IF蛋白具有序列同源性。
