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伤口愈合过程中的微血管密度变化。

Microvascular density changes during wound-healing.

作者信息

Hashimoto H, Prewitt R L

出版信息

Int J Microcirc Clin Exp. 1987;5(4):303-10.

PMID:2435668
Abstract

Vessel densities of arterioles, capillaries, venules and A-V anastomoses were determined during wound-healing following implantation of the rabbit ear chamber. Arterioles were defined on the basis of the direction of blood flow and the presence of a muscular coat. Capillaries were endothelial cell tubes with single-file flow of erythrocytes. Venules were thin-walled vessels collecting blood flow from capillaries and carrying blood flow from the tissue. A-V anastomoses were thick-walled, unbranched vessels carrying blood flow from an arteriole to a venule. Arteriolar density was relatively higher in the earlier stages but venular density was higher in the later stages of wound-healing. The fractional density was highest 2 weeks after implantation for arterioles (17.9%), at 4 weeks for capillaries (39.3%), and at 10 weeks for venules (56.9%). No significant change was observed in the density of A-V anastomoses. This study suggests that the rates of growth and decay are different among each vessel category during wound-healing.

摘要

在兔耳室植入后的伤口愈合过程中,测定了小动脉、毛细血管、小静脉和动静脉吻合支的血管密度。小动脉根据血流方向和肌层的存在来定义。毛细血管是有红细胞单行流动的内皮细胞管。小静脉是从毛细血管收集血流并将血流从组织中带走的薄壁血管。动静脉吻合支是从动脉到静脉输送血流的厚壁、无分支血管。在伤口愈合的早期阶段,小动脉密度相对较高,但在后期阶段小静脉密度较高。植入后2周小动脉的分数密度最高(17.9%),4周时毛细血管的分数密度最高(39.3%),10周时小静脉的分数密度最高(56.9%)。动静脉吻合支的密度未观察到显著变化。这项研究表明,在伤口愈合过程中,每种血管类型的生长和衰退速率是不同的。

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