Department of Chemical, Biological & Macromolecular Sciences, Unit for Nanoscience & Technology, S. N. Bose National Centre for Basic Sciences, Block JD, Sector III, Salt Lake, Kolkata 700098, India.
Nanoscale. 2014;6(3):1848-54. doi: 10.1039/c3nr05784d.
Metal clusters, composed of a few atoms at the core, exhibit unique properties and have potential applications. Although atomically precise clusters of noble metals have been synthesized, analogous systems of reactive metals, such as iron, have not been realized in solution due to high reactivity. Here we report the synthesis and characterization of novel iron clusters in the hemoglobin matrix that are highly luminescent (quantum yield 10% at 565 nm). The super-paramagnetic iron clusters, after successful ligand exchange from protein and phase transfer from water to chloroform using tri-octylphosphineoxide (TOPO), were detected as Fe₁₀(TOPO)₃(H₂O)₃, Fe₁₃(TOPO)₂(H₂O) and Fe₈(TOPO)(H₂O)₂ by mass spectrometry. This study lays the groundwork for exploiting unique properties of soluble iron clusters.
金属团簇由核心的几个原子组成，具有独特的性质，并有潜在的应用。虽然原子精确的贵金属团簇已经被合成，但类似的反应性金属（如铁）的体系由于高反应性而不能在溶液中实现。在这里，我们报告了在血红蛋白基质中合成和表征新型铁团簇，这些铁团簇具有高度的发光性（在 565nm 处的量子产率为 10%）。超顺磁铁团簇在成功地从蛋白质中进行配体交换，并使用三辛基氧化磷（TOPO）从水中转移到氯仿后，通过质谱检测到Fe₁₀(TOPO)₃(H₂O)₃、Fe₁₃(TOPO)₂(H₂O)和Fe₈(TOPO)(H₂O)₂。这项研究为利用可溶性铁团簇的独特性质奠定了基础。
