Bentler M, Stanish M
J Am Diet Assoc. 1987 Apr;87(4):488-91.
Maintaining optimal nutrition in the pediatric patient with Acquired Immune Deficiency Syndrome (AIDS) is challenging, but it may be one of the most effective therapies. Patients experience numerous complications that compromise nutritional status. Infection, fever, diarrhea, feeding problems, and decreased intake all contribute to malnutrition, which in turn predisposes the patient even more to infection and malabsorption. Nutrition assessment should be done routinely so that new problems may be identified and treated. High-calorie, high-protein feedings, vitamin supplementation, and, when necessary, gavage feedings or parenteral nutrition are recommended to improve nutritional status and prevent further deficits. Maintaining optimal nutrition in the pediatric patient with Acquired Immune Deficiency Syndrome (AIDS) poses a significant challenge to the health care team. Patients may experience numerous complications that compromise nutritional status. The patient is at high risk for opportunistic infections, especially of the lungs, central nervous system, gastrointestinal (GI) tract, and skin. Such infections are common causes of morbidity and mortality. Impaired nutritional status may further impair the patient's immunocompetence. A study by Kotler and Gaety demonstrated severe progressive malnutrition in adult AIDS patients, with the lowest measures of lean body mass occurring in those patients close to death at the time of the study. While no studies of children with AIDS have been done to date, we have subjectively observed feeding problems, weight loss, and malnutrition in most of the patients we have seen.
在患有获得性免疫缺陷综合征(艾滋病)的儿科患者中维持最佳营养状况具有挑战性,但这可能是最有效的治疗方法之一。患者会出现许多影响营养状况的并发症。感染、发热、腹泻、喂养问题和摄入量减少都会导致营养不良,而营养不良反过来又会使患者更容易感染和出现吸收不良。应定期进行营养评估,以便发现并治疗新出现的问题。建议采用高热量、高蛋白饮食,补充维生素,必要时进行管饲或肠外营养,以改善营养状况并防止进一步的营养缺乏。在患有获得性免疫缺陷综合征(艾滋病)的儿科患者中维持最佳营养状况对医疗团队构成了重大挑战。患者可能会出现许多影响营养状况的并发症。患者发生机会性感染的风险很高,尤其是肺部、中枢神经系统、胃肠道和皮肤的感染。此类感染是发病和死亡的常见原因。营养状况受损可能会进一步损害患者的免疫能力。科特勒和盖蒂的一项研究表明,成年艾滋病患者存在严重的进行性营养不良,在研究时接近死亡的患者中瘦体重测量值最低。虽然迄今为止尚未对艾滋病儿童进行研究,但我们主观观察到,在我们所诊治的大多数患者中都存在喂养问题、体重减轻和营养不良的情况。