Benkov K J, Stawski C, Sirlin S M, Klapholz M B, Siegal F, LeLeiko N S
Am J Gastroenterol. 1985 Apr;80(4):260-5.
A child with acquired immune deficiency syndrome became severely malnourished presumably as a result of multiple gastrointestinal infections, with numerous organisms including campylobacter, giardia, and cryptosporidium. These opportunistic infections preceded laboratory evidence of immune deficiency. Despite severe diarrhea and marked weight loss, there was no laboratory evidence of significant malabsorption. By using nasogastric feedings, we were successful in promoting a 60% weight gain, and a rise in serum albumin from 1.2 to 4.3 g/dl. While eventual outcome was not altered, this particular patient's clinical course was improved. We suggest that malnutrition should not be accepted as inevitable and that malabsorption should not be assumed in similar acquired immune deficiency syndrome patients. Appropriate studies for malabsorption should be done, and high caloric enteral feedings should be used whenever feasible.
一名患有获得性免疫缺陷综合征的儿童出现了严重营养不良，推测这是多种胃肠道感染的结果，感染的病原体众多，包括弯曲杆菌、贾第虫和隐孢子虫。这些机会性感染先于免疫缺陷的实验室证据出现。尽管有严重腹泻和明显体重减轻，但实验室检查并无明显吸收不良的证据。通过鼻饲喂养，我们成功使患儿体重增加了60%，血清白蛋白从1.2克/分升升至4.3克/分升。虽然最终结局未改变，但该患儿的临床病程得到了改善。我们建议，不应将营养不良视为不可避免，对于类似的获得性免疫缺陷综合征患者，不应假定存在吸收不良。应进行适当的吸收不良相关检查，并且只要可行，就应使用高热量肠内喂养。
