Murnyák Balázs, Csonka Tamás, Klekner Almos, Hortobágyi Tibor
Debreceni Egyetem, Orvos- és Egészségtudományi Centrum, Neuropatológiai Tanszék, Debrecen.
Debreceni Egyetem, Orvos- és Egészségtudományi Centrum, Idegsebészeti Klinika, Debrecen.
Ideggyogy Sz. 2013 Sep 30;66(9-10):305-11.
The WHO grade I. and II. low-grade gliomas represent nearly the 15% of all primary brain tumors. These tumours contain clinically, histologically and molecularly distinct tumor types. According to their histologic characteristic, grade II glial tumours are the diffuse astrocytoma, oligodendroglioma and oligoastrocytoma subgroups; ependymal tumors are not included in this study.
In our publication, we analysed the histologically diagnosed glioma cases between 2007 and 2011 at our institution.
Low-grade gliomas were diagnosed in 127 cases (62 male / 65 female), and the mean ages were 39 years (+/- 20.3). More than half of the cancers were localized in the frontal lobe, and the second most frequent area was the temporal lobe. Finally, we complete our report with an overview of major molecular pathways in low-grade gliomas.
世界卫生组织一级和二级低级别胶质瘤约占所有原发性脑肿瘤的15%。这些肿瘤包含临床上、组织学上和分子水平上不同的肿瘤类型。根据组织学特征，二级胶质肿瘤为弥漫性星形细胞瘤、少突胶质细胞瘤和少突星形细胞瘤亚组；室管膜瘤不包括在本研究中。
在我们的出版物中，我们分析了2007年至2011年在我们机构经组织学诊断的胶质瘤病例。
诊断出127例低级别胶质瘤（男性62例/女性65例），平均年龄为39岁（±20.3）。超过一半的肿瘤位于额叶，第二常见的部位是颞叶。最后，我们通过概述低级别胶质瘤的主要分子途径来完成我们的报告。
