Tan Yi, Zhou Hong-xia, Wang Yi-guang, Gan Mao-luo, Yang Zhao-yong
Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Yao Xue Xue Bao. 2013 Sep;48(9):1369-75.
In the last decade, along with the development of taxonomy research in marine-derived actinobacteria, more and more halogenated natural products were discovered from marine actinobacteria. Most of them showed good biological activity and unique structure compared to those from land. The special halogenation mechanism in some compounds' biosynthesis has drawn great attention. So in this review, we focus on the halogenated natural products from marine actinobacteria and their halogenation mechanisms.
在过去十年中，随着海洋来源放线菌分类学研究的发展，越来越多的卤代天然产物从海洋放线菌中被发现。与陆地来源的卤代天然产物相比，它们中的大多数表现出良好的生物活性和独特的结构。一些化合物生物合成中特殊的卤化机制引起了极大关注。因此，在本综述中，我们聚焦于海洋放线菌来源的卤代天然产物及其卤化机制。
