Akil A, Api O, Bektas Y, Yilmaz A Onan, Yalti S, Unal O
Bodrum Acıbadem Hospital , Bodrum , Mugla.
J Obstet Gynaecol. 2014 Jan;34(1):25-8. doi: 10.3109/01443615.2013.828026.
A randomised controlled trial was conducted to investigate efficacy of paracetamol and dexketoprofen trometamol for perineal pain relief after perineal repair. Subjects were randomly assigned to receive two doses of either 50 mg of intravenous dexketoprofen trometamol via slow i.v. infusion (Group I, n = 49) or 1,000 mg of paracetamol via intravenous infusion (Group II, n = 46). The main outcome measure was a VAS (visual analogue scale) for pain recorded at 1 h (VAS 1). A total of 82 patients were included in the final analysis (Group I, n = 41; Group II, n = 41). There was no difference among groups in terms of pain scores at the beginning (VAS 0). The pain was decreased in 70% of the patients in Group I and in 62% of the patients in Group II (p = 0.502). Both paracetamol and dexketoprofen are effective in perineal pain relief after episiotomy or perineal tear repair.
进行了一项随机对照试验，以研究对乙酰氨基酚和右酮洛芬氨丁三醇缓解会阴修补术后会阴疼痛的疗效。受试者被随机分配接受两剂药物，即通过静脉缓慢输注50mg静脉注射用右酮洛芬氨丁三醇（第一组，n = 49）或通过静脉输注1000mg对乙酰氨基酚（第二组，n = 46）。主要结局指标是在1小时记录的疼痛视觉模拟量表（VAS）（VAS 1）。共有82例患者纳入最终分析（第一组，n = 41；第二组，n = 41）。各组在开始时的疼痛评分（VAS 0）方面无差异。第一组70%的患者疼痛减轻，第二组62%的患者疼痛减轻（p = 0.502）。对乙酰氨基酚和右酮洛芬在会阴切开术或会阴撕裂修补术后缓解会阴疼痛方面均有效。
