[一例产生甲胎蛋白（AFP）的子宫癌肉瘤病例报告]
[A case report of uterine carcinosarcoma with alpha-fetoprotein (AFP) production].
作者信息
Shigemasa K, Myoga H, Nakanishi Y, Imajo M, Yorishima M, Matsuda H, Hung C C, Egawa K, Katsube Y, Fujiwara A
出版信息
Gan No Rinsho. 1987 Feb;33(2):223-9.
A case of carcinosarcoma, mixture of endometrial stromal sarcoma and adenocarcinoma, of the uterus with alpha-fetoprotein (AFP) production in a 69-year-old woman was reported. By the results of serum AFP levels (preoperative: 2,950.0 ng/ml, post-operative and chemotherapy: 2.1 ng/ml) and immunohistochemical localization of AFP, the AFP was thought to be produced from this tumor. Immunoreactive AFP was found in the carcinomatous components and no AFP was present in the sarcomatous components at all. It seems from this that immunohistochemical study supports the composition theory of mixed mullerian sarcoma of the uterus.
报告了一例69岁女性子宫癌肉瘤（子宫内膜间质肉瘤和腺癌的混合体）伴甲胎蛋白（AFP）产生的病例。根据血清AFP水平结果（术前：2950.0 ng/ml，术后及化疗后：2.1 ng/ml）以及AFP的免疫组化定位，认为AFP由该肿瘤产生。在癌性成分中发现了免疫反应性AFP，而肉瘤性成分中完全没有AFP。由此看来，免疫组化研究支持子宫混合性苗勒氏肉瘤的成分理论。
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