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血管腔内腹主动脉瘤修复术后出院后结局

Postdischarge outcomes after endovascular abdominal aortic aneurysm repair.

作者信息

Gupta Prateek K, Engelbert Travis L, Ramanan Bala, Fang Xiang, Yamanouchi Dai, Hoch John R, Acher Charles W

机构信息

Department of Surgery, University of Wisconsin Hospital and Clinics, Madison, Wisc.

Department of Surgery, University of Wisconsin Hospital and Clinics, Madison, Wisc.

出版信息

J Vasc Surg. 2014 Apr;59(4):903-8. doi: 10.1016/j.jvs.2013.10.057. Epub 2013 Dec 17.

Abstract

OBJECTIVE

Perioperative outcomes after endovascular repair (EVAR) of abdominal aortic aneurysms (AAA) have been rigorously studied; however, inpatient and postdischarge outcomes have not been separately analyzed. The objective of this study was to examine postdischarge 30-day outcomes after elective EVAR.

METHODS

Patients who underwent an elective EVAR for AAA (n = 11,229) were identified from the American College of Surgeons 2005-2010 National Surgical Quality Improvement Project database. Univariable and multivariable logistic regression analyses were performed.

RESULTS

The median length of hospital stay was 2 days (interquartile range, 1-3 days). Overall 30-day mortality was 1.0% (n = 117), with 31% (n = 36) of the patients dying after discharge. Overall 30-day morbidity was 10.7% (n = 1204), with 40% (n = 500) of the morbidities being postdischarge. The median time of death and complication was 9 and 3 days, respectively, after surgery. Eighty-eight percent of the wound infections (n = 205 of 234), 33% of pneumonia (n = 44 of 133), and 55% of venous thromboembolism (n = 36 of 65) were postdischarge. Multivariable analyses showed age, congestive heart failure, admission from nursing facility, postoperative pneumonia, myocardial infarction, and renal failure were independently associated with postdischarge mortality, and peripheral arterial disease, female gender, previous cardiac surgery, age, smoking, and diabetes with postdischarge morbidity (P < .05 for all).

CONCLUSIONS

Patient characteristics associated with a higher risk for postdischarge adverse events after EVAR were identified. Whether improved predischarge surveillance and close postdischarge follow-up of identified high-risk patients will further improve 30-day outcomes after EVAR needs to be prospectively studied.

摘要

目的

腹主动脉瘤(AAA)血管腔内修复术(EVAR)后的围手术期结局已得到深入研究;然而,住院期间及出院后的结局尚未分别进行分析。本研究的目的是探讨择期EVAR术后出院后30天的结局。

方法

从美国外科医师学会2005 - 2010年国家外科质量改进项目数据库中识别出接受择期AAA-EVAR手术的患者(n = 11229)。进行单变量和多变量逻辑回归分析。

结果

住院时间中位数为2天(四分位间距,1 - 3天)。30天总死亡率为1.0%(n = 117),其中31%(n = 36)的患者在出院后死亡。30天总发病率为10.7%(n = 1204),其中40%(n = 500)的发病发生在出院后。术后死亡和并发症的中位时间分别为9天和3天。88%(234例中的205例)的伤口感染、33%(133例中的44例)的肺炎以及55%(65例中的36例)的静脉血栓栓塞发生在出院后。多变量分析显示,年龄、充血性心力衰竭、从护理机构入院、术后肺炎、心肌梗死和肾衰竭与出院后死亡率独立相关,而外周动脉疾病、女性性别、既往心脏手术、年龄、吸烟和糖尿病与出院后发病率相关(所有P < 0.05)。

结论

确定了与EVAR术后出院后不良事件高风险相关的患者特征。对于已识别出的高危患者,改进出院前监测和出院后密切随访是否会进一步改善EVAR术后30天结局,有待前瞻性研究。

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