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血管免疫母细胞性淋巴结病的病毒病因学研究。

Studies on viral etiology of angioimmunoblastic lymphadenopathy.

作者信息

Szabó B, Váczi L, Tóth F D, Pálóczy K, Szegedi G

出版信息

Neoplasma. 1987;34(1):67-72.

PMID:2436065
Abstract

Plasma samples of patients with angioimmunoblastic lymphadenopathy (AIBL) were tested for anti-HTLV antibodies and for interferon content. Out of 12 patients 4 had antibodies to HTL-III. Two of these plasma samples contained antibodies reacting with HTLV-I and HTLV-II, too. Activated interferon (IFN) system was found in patients with clinical remission of AIBL, as it was detected by IFN titration in their plasma samples. Data suggest the etiological role in AIBL of virus(es) related to the HTLV family.

摘要

对血管免疫母细胞性淋巴结病(AIBL)患者的血浆样本进行了抗人嗜T淋巴细胞病毒(HTLV)抗体和干扰素含量检测。12名患者中有4名具有抗HTL-III抗体。其中两份血浆样本还含有与HTLV-I和HTLV-II发生反应的抗体。在AIBL临床缓解的患者中发现了激活的干扰素(IFN)系统,这是通过对其血浆样本进行IFN滴定检测到的。数据表明与HTLV家族相关的病毒在AIBL发病机制中具有病因学作用。

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