爱泼斯坦-巴尔病毒与血管免疫母细胞性淋巴结病样淋巴增殖综合征的关联。
Association of Epstein-Barr virus with an angioimmunoblastic lymphadenopathy-like lymphoproliferative syndrome.
作者信息
White A C, Katz B Z, Silbert J A
机构信息
Department of Medicine, Yale University School of Medicine, New Haven, Connecticut 06510.
出版信息
Yale J Biol Med. 1989 May-Jun;62(3):263-9.
A patient presented with fever, night sweats, generalized lymphadenopathy, cold agglutinin hemolytic anemia, and thrombocytopenia. Lymph node biopsy revealed a lymphoplasmacytic infiltrate sparing the cortical sinuses but associated with arborizing blood vessels. Epstein-Barr virus (EBV) DNA was demonstrated in tissue from an involved lymph node. These data suggest an association of EBV with a lymphoproliferative process that resembles angioimmunoblastic lymphadenopathy with dysproteinemia.
一名患者出现发热、盗汗、全身淋巴结病、冷凝集素溶血性贫血和血小板减少症。淋巴结活检显示淋巴细胞浆细胞浸润，不累及皮质窦，但与树枝状血管相关。在受累淋巴结组织中检测到爱泼斯坦-巴尔病毒（EBV）DNA。这些数据表明EBV与一种类似于伴有蛋白异常血症的血管免疫母细胞性淋巴结病的淋巴增殖过程有关。
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