Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Baltimore, Maryland.
Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Baltimore, Maryland; University of Miami Miller School of Medicine, Miami, Florida.
Am J Cardiol. 2014 Feb 15;113(4):637-43. doi: 10.1016/j.amjcard.2013.11.010. Epub 2013 Nov 23.
Physical activity and cardiorespiratory fitness are associated with improved cardiovascular health and reduced all-cause mortality. The relation between self-reported physical activity, objective physical fitness, and the association of each with cardiometabolic risk has not been fully described. We studied 2,800 healthy Brazilian subjects referred for an employer-sponsored health screening. Physical activity level was determined as "low," "moderate," or "high" with the International Physical Activity Questionnaire: Short Form (IPAQ-SF). Fitness was measured as METs achieved on a maximal, symptom-limited, treadmill stress test. Using multivariate linear regression analysis, we calculated age, gender, and smoking-adjusted correlation coefficients among IPAQ-SF, fitness, and cardiometabolic risk factors. Mean age of study participants was 43 ± 9 years; 81% were men, and 43% were highly active. Mean METs achieved was 12 ± 2. IPAQ-SF category and fitness were moderately correlated (r = 0.377). Compared with IPAQ-SF category, fitness was better correlated with cardiometabolic risk factors including anthropomorphic measurements, blood pressure, fasting blood glucose, dyslipidemia, high-sensitivity C-reactive protein, and hepatic steatosis (all p <0.01). Among these, anthropomorphic measurements, blood pressure, high-sensitivity C-reactive protein, and hepatic steatosis had the largest discrepancies in correlation, whereas lipid factors had the least discrepant correlation. When IPAQ-SF and fitness were discordant, poor fitness drove associations with elevated cardiometabolic risk. In conclusion, self-reported physical activity level and directly measured fitness are moderately correlated, and the latter is more strongly associated with a protective cardiovascular risk profile.
身体活动和心肺适能与改善心血管健康和降低全因死亡率有关。自我报告的身体活动、客观的身体体能与每种身体活动和心血管代谢风险之间的关联尚未完全描述。我们研究了 2800 名健康的巴西受试者，他们被推荐参加雇主赞助的健康筛查。身体活动水平通过国际身体活动问卷：短表（IPAQ-SF）确定为“低”、“中”或“高”。体能通过在最大、症状限制的跑步机压力测试中达到的 METs 来测量。使用多元线性回归分析，我们计算了 IPAQ-SF、体能和心血管代谢危险因素之间的年龄、性别和吸烟调整后的相关系数。研究参与者的平均年龄为 43 ± 9 岁；81%为男性，43%为高度活跃。平均达到的 METs 为 12 ± 2。IPAQ-SF 类别和体能之间存在中度相关性（r = 0.377）。与 IPAQ-SF 类别相比，体能与心血管代谢危险因素的相关性更好，包括人体测量学指标、血压、空腹血糖、血脂异常、高敏 C 反应蛋白和肝脂肪变性（均 p <0.01）。在这些因素中，人体测量学指标、血压、高敏 C 反应蛋白和肝脂肪变性的相关性差异最大，而血脂因素的相关性差异最小。当 IPAQ-SF 和体能不一致时，体能不佳会导致与升高的心血管代谢风险相关联。总之，自我报告的身体活动水平和直接测量的体能呈中度相关，后者与保护性心血管风险特征的关联更强。
