Wu Wenqi, Yang Bicheng, Ou Lili, Liang Yeping, Wan Shawpong, Li Shujue, Zeng Guohua
Department of Urology, Minimally Invasive Surgery Center, The First Affiliated Hospital of Guangzhou Medical University, Guangdong Key Laboratory of Urology, 1# Kangda Road, Haizhu District, Guangzhou, 510230, China.
Urolithiasis. 2014 Feb;42(1):39-43. doi: 10.1007/s00240-013-0633-0. Epub 2013 Dec 22.
We reported a retrospective review of the urinary stone compositions in 12,846 patients. Data on urinary stone compositions analyzed between January 2003 and December 2012 in our center were collected. Infrared spectroscopy was used for stone analysis. Predominant stone component was recorded. Patients were divided into four age groups: 0-18, 19-40, 41-60, and 61-92, and five categories by components. In order to determine the change of stone characteristics with respect to time, data were also divided into two periods, 2003-2007 and 2008-2012. A total of 12,846 stones were included in this study. The age of the patients ranged from 1 to 92 years with 7,736 males and 5,110 females. Stone made of single component was rare, 2.61%. Calcium oxalate stone was the most common component at 82.56%. Calcium oxalate and uric acid stones were more common in male than in female. The incidence of calcium phosphate stones and uric acid stones had increased during the past 5 years, while calcium oxalate stones decreased. We found the highest incidence of stone disease in the 41-60 years old group and the lowest in the 1-18 years old for both genders. Calcium oxalate was the dominant component in every group but was more prevalent in 19-40 years group. The percentage of magnesium ammonium phosphate stone and uric acid stone increased with age.
我们报告了对12846例患者尿结石成分的回顾性研究。收集了2003年1月至2012年12月期间在我们中心分析的尿结石成分数据。采用红外光谱法进行结石分析。记录主要结石成分。患者按年龄分为四个组:0 - 18岁、19 - 40岁、41 - 60岁和61 - 92岁,并按成分分为五类。为了确定结石特征随时间的变化,数据还分为两个时期,2003 - 2007年和2008 - 2012年。本研究共纳入12846颗结石。患者年龄范围为1至92岁,男性7736例,女性5110例。单成分结石很少见,占2.61%。草酸钙结石是最常见的成分,占82.56%。草酸钙结石和尿酸结石在男性中比在女性中更常见。在过去5年中,磷酸钙结石和尿酸结石的发病率有所增加,而草酸钙结石有所减少。我们发现,41 - 60岁年龄组的结石病发病率最高,1 - 18岁年龄组的发病率最低,男女皆是如此。草酸钙是每个组中的主要成分,但在19 - 40岁年龄组中更为普遍。磷酸镁铵结石和尿酸结石的百分比随年龄增长而增加。