Department of Urology, Chengdu Second People's Hospital, Chengdu, China.
Eur Rev Med Pharmacol Sci. 2024 May;28(9):3447-3454. doi: 10.26355/eurrev_202405_36190.
This study aimed to quantitatively analyze the calculi components of upper urinary tract calculi and to explore the relationship between calculus components, demographic characteristics, and underlying diseases.
Clinical data of 1,495 patients with upper urinary tract calculi were retrospectively collected. The calculi were divided into simple calcium oxalate, calcium oxalate mixed, calcium phosphate mixed, uric acid, magnesium ammonium phosphate, and other components. Statistical software SPSS 22.0 was used to analyze the differences between the stone compositions and various factors. The influencing factors (p < 0.05) were analyzed using multiple logistic regression analysis.
Among 1,495 patients with upper urinary tract calculi, simple calcium oxalate calculi were the most common component (39.7%), followed by calcium oxalate mixed calculi (30.4%), uric acid calculi (13.6%), calcium phosphate mixed calculi (10.4%), magnesium ammonium phosphate calculi (5.8%) and other component calculi (0.1%). Univariate analysis revealed statistically significant differences in stone composition according to gender, age, and hyperuricemia (p < 0.05). Multiple logistic regression analysis showed that compared to men, the odds ratio (OR) values of calcium oxalate mixed stones, calcium phosphate mixed stones, and magnesium ammonium phosphate stones in women were 1.61, 2.50, and 4.17, respectively (p < 0.001). Compared with elderly patients, the OR values of calcium phosphate mixed stones in young and middle-aged patients were 3.14 and 2.70, respectively (p < 0.05).
Patients with different stone components had different demographic characteristics, and stone components were significantly different between gender and age. Calcium oxalate mixed stones were more common in females, and calcium phosphate mixed stones and magnesium ammonium phosphate stones were more common in females, young patients, and middle-aged patients.
本研究旨在定量分析上尿路结石的结石成分，并探讨结石成分与人口统计学特征和基础疾病之间的关系。
回顾性收集 1495 例上尿路结石患者的临床资料。将结石分为单纯草酸钙、草酸钙混合、磷酸钙混合、尿酸、碳酸铵镁和其他成分。采用统计软件 SPSS 22.0 分析结石成分与各种因素之间的差异。采用多因素 logistic 回归分析影响因素（p＜0.05）。
在 1495 例上尿路结石患者中，单纯草酸钙结石最为常见（39.7%），其次为草酸钙混合结石（30.4%）、尿酸结石（13.6%）、磷酸钙混合结石（10.4%）、碳酸铵镁结石（5.8%）和其他成分结石（0.1%）。单因素分析显示，结石成分在性别、年龄和高尿酸血症方面存在统计学差异（p＜0.05）。多因素 logistic 回归分析显示，与男性相比，女性草酸钙混合结石、磷酸钙混合结石和碳酸铵镁结石的优势比（OR）值分别为 1.61、2.50 和 4.17（p＜0.001）。与老年患者相比，年轻和中年患者磷酸钙混合结石的 OR 值分别为 3.14 和 2.70（p＜0.05）。
不同结石成分的患者具有不同的人口统计学特征，性别和年龄之间结石成分存在显著差异。草酸钙混合结石在女性中更为常见，而磷酸钙混合结石和碳酸铵镁结石在女性、年轻患者和中年患者中更为常见。
