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胶囊内镜在婴幼儿中的安全性和实用性。

Safety and utility of capsule endoscopy for infants and young children.

机构信息

Manari Oikawa-Kawamoto, Tsuyoshi Sogo, Takeshi Yamaguchi, Tomoyuki Tsunoda, Takeo Kondo, Department of Pediatric Hepatology and Gastroenterology and Endoscopy Center, Saiseikai Yokohama City Tobu Hospital, Yokohama, Kanagawa 230-0012, Japan.

出版信息

World J Gastroenterol. 2013 Dec 7;19(45):8342-8. doi: 10.3748/wjg.v19.i45.8342.

Abstract

AIM

To assess the safety and utility of capsule endoscopy (CE) for children who are unable to swallow the capsule endoscope.

METHODS

The medical records of all of the children who underwent CE between 2010 and 2012 were retrospectively reviewed. The patients were divided into 2 groups: group A included patients who were unable to swallow the capsule endoscope, and group B included patients who were able to swallow it. For the patients who were unable to swallow the capsule endoscope, it was placed in the duodenum endoscopically. The small bowel transit time, endoscopic diagnosis and complications of the 2 groups were compared.

RESULTS

During the study period, 28 CE procedures were performed in 26 patients. Group A included 11 patients with a median age of 2 years (range 10 mo-9 years), and group B included 15 patients with a median age of 12 years (range 8 years-16 years). The lightest child in the study weighed 7.9 kg. The detection rates did not differ between the 2 groups. The median small bowel transit time was 401 min (range 264-734 min) in group A and 227 min (range 56-512 min) in group B (P = 0.0078). No serious complications, including capsule retention, occurred. No significant mucosal trauma occurred in the pharynx, esophagus, stomach or duodenum when the capsule was introduced using an endoscope.

CONCLUSION

CE is a safe and useful procedure for infants and young children who are unable to swallow the capsule endoscope.

摘要

目的

评估胶囊内镜(CE)在不能吞咽胶囊内镜的儿童中的安全性和实用性。

方法

回顾性分析 2010 年至 2012 年间所有接受 CE 检查的儿童的病历。患者分为 2 组:A 组为不能吞咽胶囊内镜的患者,B 组为能够吞咽胶囊内镜的患者。对于不能吞咽胶囊内镜的患者,将胶囊内镜经内镜置于十二指肠内。比较两组患者的小肠通过时间、内镜诊断和并发症。

结果

研究期间,26 例患者共进行了 28 例 CE 检查。A 组 11 例,中位年龄 2 岁(范围 10 个月-9 岁);B 组 15 例,中位年龄 12 岁(范围 8 岁-16 岁)。研究中体重最轻的患儿为 7.9kg。两组的检出率无差异。A 组小肠通过时间中位数为 401min(范围 264-734min),B 组为 227min(范围 56-512min)(P=0.0078)。两组均无严重并发症,包括胶囊滞留。当使用内镜将胶囊引入时,咽、食管、胃和十二指肠均未发生明显的黏膜创伤。

结论

对于不能吞咽胶囊内镜的婴幼儿,CE 是一种安全且有用的检查方法。

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