使用基于模型的定义重新审视“低出生体重悖论”。
Revisiting the 'Low BirthWeight paradox' using a model-based definition.
作者信息
Juárez Sol, Ploubidis George B, Clarke Lynda
机构信息
Centre for Economic Demography, Lund University, Lund, Sweden.
Department of Population Studies, London School of Hygiene and Tropical Medicine, London, United Kingdom.
出版信息
Gac Sanit. 2014 Mar-Apr;28(2):160-2. doi: 10.1016/j.gaceta.2013.08.001. Epub 2013 Dec 21.
INTRODUCTION
Immigrant mothers in Spain have a lower risk of delivering Low BirthWeight (LBW) babies in comparison to Spaniards (LBW paradox). This study aimed at revisiting this finding by applying a model-based threshold as an alternative to the conventional definition of LBW.
METHODS
Vital information data from Madrid was used (2005-2006). LBW was defined in two ways (less than 2500g and Wilcox's proposal). Logistic and linear regression models were run.
RESULTS
According to common definition of LBW (less than 2500g) there is evidence to support the LBW paradox in Spain. Nevertheless, when an alternative model-based definition of LBW is used, the paradox is only clearly present in mothers from the rest of Southern America, suggesting a possible methodological bias effect.
CONCLUSION
In the future, any examination of the existence of the LBW paradox should incorporate model-based definitions of LBW in order to avoid methodological bias.
引言
与西班牙本土母亲相比，西班牙的移民母亲生下低体重婴儿的风险更低（低体重悖论）。本研究旨在通过应用基于模型的阈值重新审视这一发现，以此替代低体重的传统定义。
方法
使用了来自马德里的生命信息数据（2005 - 2006年）。低体重通过两种方式定义（低于2500克和威尔科克斯的提议）。运行了逻辑回归和线性回归模型。
结果
根据低体重的常见定义（低于2500克），有证据支持西班牙存在低体重悖论。然而，当使用基于模型且替代的低体重定义时，该悖论仅在来自南美洲其他地区的母亲中明显存在，这表明可能存在方法学上的偏差效应。
结论
未来，任何对低体重悖论存在情况的研究都应纳入基于模型的低体重定义，以避免方法学上的偏差。
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