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1
Causes and consequences of replication stress.
Nat Cell Biol. 2014 Jan;16(1):2-9. doi: 10.1038/ncb2897.
2
The ATR pathway: fine-tuning the fork.
DNA Repair (Amst). 2007 Jul 1;6(7):953-66. doi: 10.1016/j.dnarep.2007.02.015. Epub 2007 May 24.
5
Mutations in DONSON disrupt replication fork stability and cause microcephalic dwarfism.
Nat Genet. 2017 Apr;49(4):537-549. doi: 10.1038/ng.3790. Epub 2017 Feb 13.
6
Stalled replication forks: making ends meet for recognition and stabilization.
Bioessays. 2010 Aug;32(8):687-97. doi: 10.1002/bies.200900196.
7
ATM and ATR promote Mre11 dependent restart of collapsed replication forks and prevent accumulation of DNA breaks.
EMBO J. 2006 Apr 19;25(8):1764-74. doi: 10.1038/sj.emboj.7601045. Epub 2006 Apr 6.
9
The BRUCE-ATR Signaling Axis Is Required for Accurate DNA Replication and Suppression of Liver Cancer Development.
Hepatology. 2019 Jun;69(6):2608-2622. doi: 10.1002/hep.30529. Epub 2019 Mar 13.
10
UV-induced ataxia-telangiectasia-mutated and Rad3-related (ATR) activation requires replication stress.
J Biol Chem. 2004 Mar 12;279(11):9677-80. doi: 10.1074/jbc.C300554200. Epub 2004 Jan 23.

引用本文的文献

1
SLFN11, far from being limited to responding to cancer DNA damage.
Clin Exp Med. 2025 Aug 26;25(1):304. doi: 10.1007/s10238-025-01776-y.
2
DNA double-strand break end resection factors and WRN facilitate mitotic DNA synthesis in human cells.
Nat Commun. 2025 Aug 25;16(1):7901. doi: 10.1038/s41467-025-63292-7.
3
Wnt10b signaling regulates replication stress-induced chromosomal instability in human cancer.
Life Sci Alliance. 2025 Aug 22;8(11). doi: 10.26508/lsa.202503295. Print 2025 Nov.
5
Fission yeast Rad54 prevents intergenerational buildup of Rad51 aggregates in proliferating cells.
Life Sci Alliance. 2025 Aug 18;8(11). doi: 10.26508/lsa.202503252. Print 2025 Nov.
7
The Ski2 helicase ASCC3 unwinds DNA upon fork stalling to control replication stress responses.
bioRxiv. 2025 Jul 26:2025.07.24.666583. doi: 10.1101/2025.07.24.666583.
8
Protein arginine methylation regulates anti-inflammatory programming in response to aging stress.
iScience. 2025 Jul 10;28(8):113095. doi: 10.1016/j.isci.2025.113095. eCollection 2025 Aug 15.
9
Mono-ADP-ribosylating PARP enzymes in cellular signaling and disease.
J Cell Sci. 2025 Jul 15;138(14). doi: 10.1242/jcs.263963. Epub 2025 Jul 31.

本文引用的文献

1
Senataxin protects the genome: Implications for neurodegeneration and other abnormalities.
Rare Dis. 2013 Jun 6;1:e25230. doi: 10.4161/rdis.25230. eCollection 2013.
2
RNF4 and PLK1 are required for replication fork collapse in ATR-deficient cells.
Genes Dev. 2013 Oct 15;27(20):2259-73. doi: 10.1101/gad.223180.113.
3
How unfinished business from S-phase affects mitosis and beyond.
EMBO J. 2013 Oct 16;32(20):2661-71. doi: 10.1038/emboj.2013.211. Epub 2013 Sep 24.
4
Two replication fork maintenance pathways fuse inverted repeats to rearrange chromosomes.
Nature. 2013 Sep 26;501(7468):569-72. doi: 10.1038/nature12500. Epub 2013 Sep 8.
5
DNA damage sensing by the ATM and ATR kinases.
Cold Spring Harb Perspect Biol. 2013 Sep 1;5(9):a012716. doi: 10.1101/cshperspect.a012716.
6
NEK8 links the ATR-regulated replication stress response and S phase CDK activity to renal ciliopathies.
Mol Cell. 2013 Aug 22;51(4):423-39. doi: 10.1016/j.molcel.2013.08.006.
8
Causes of genome instability.
Annu Rev Genet. 2013;47:1-32. doi: 10.1146/annurev-genet-111212-133232. Epub 2013 Jul 31.
9
Stepwise activation of the ATR signaling pathway upon increasing replication stress impacts fragile site integrity.
PLoS Genet. 2013;9(7):e1003643. doi: 10.1371/journal.pgen.1003643. Epub 2013 Jul 18.
10
ATR phosphorylates SMARCAL1 to prevent replication fork collapse.
Genes Dev. 2013 Jul 15;27(14):1610-23. doi: 10.1101/gad.214080.113.

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