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Fibrodysplasia ossificans progressiva: a case report.

作者信息

Dhamangaonkar Anoop C, Tawari Akhil A, Goregaonkar Arvind B

机构信息

Department of Orthopaedics, Lokmanya Tilak Municipal General Hospital and Lokmanya Tilak Municipal Medical College, Sion, Mumbai, Maharashtra, India.

出版信息

J Orthop Surg (Hong Kong). 2013 Dec;21(3):383-6. doi: 10.1177/230949901302100325.

DOI:10.1177/230949901302100325
PMID:24366806
Abstract

Fibrodysplasia ossificans progressiva or myositis ossificans is a rare disease characterised by bony deposits or the ossification of soft tissues. It transforms skeletal muscles, tendons, ligaments, fascia, and aponeuroses into heterotopic bony deposits through an endochondral process. This leads to progressive immobility; patients are usually wheelchair-bound by the second decade of life and die of thoracic insufficiency by the fourth decade of life. There is no treatment apart from symptomatic treatment with steroids during flare-ups. Excision of heterotopic ossification is not recommended as it can provoke extensive and painful new growths. It is important to detect the disease early from characteristic signs of great toe abnormalities and heterotopic ossifications to improve quality of life through early physiotherapy.

摘要

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