Chaabane K, Turki E, Zouari F, Charfi S, Guermazi M, Mhiri C
Rev Med Interne. 2013 Nov;34(11):713-5. doi: 10.1016/j.revmed.2013.02.005. Epub 2013 Oct 23.
Paraneoplastic cerebellar degeneration may be a manifestation indicative of lung, gynecological or breast cancer. Nevertheless, breast cancer is rarely revealed by the occurrence of a paraneoplastic syndrome.
We report a 38-year-old patient who presented a paraneoplastic cerebellar degeneration with anti-Yo antibodies as the presenting manifestation of a breast cancer.
The diagnosis of a paraneoplastic neurological syndrome (PNS) should lead to urgent and comprehensive screening for cancer oriented by the type of PNS and the nature of the anti-neuronal antibody.
副肿瘤性小脑变性可能是肺癌、妇科癌症或乳腺癌的一种表现。然而,副肿瘤综合征很少提示乳腺癌。
我们报告一名38岁患者,其以抗Yo抗体阳性的副肿瘤性小脑变性作为乳腺癌的首发表现。
副肿瘤性神经综合征(PNS)的诊断应根据PNS的类型和抗神经元抗体的性质,进行紧急、全面的癌症筛查。