Wu Douglas C, Salopek Thomas G
Division of Dermatology, Department of Medicine, University of Alberta, Edmonton, AB, Canada T6G 2G3.
Division of Dermatology, Department of Medicine, University of Alberta, Edmonton, AB, Canada T6G 2G3 ; Division of Dermatology and Cutaneous Sciences, Department of Medicine, University of Alberta, 2-125 Clinical Sciences Building, Edmonton, AB, Canada T6G 2G3.
Case Rep Dermatol Med. 2013;2013:762035. doi: 10.1155/2013/762035. Epub 2013 Dec 4.
We report a patient with recalcitrant folliculitis decalvans who was placed on infliximab due to failure to respond to numerous immunosuppressive drugs and antibiotics. After the second infusion of infliximab the patient reported a cutaneous eruption to the bilateral groin, penis, scrotum, perineum, and perianal region consistent with genital warts. The case highlights the need to inquire about a past or current history of genital or anal warts prior to the initiation of anti-TNF therapy, particularly with infliximab. If present, consideration should be given to concurrent antiwart therapy.
我们报告了一名患有顽固性脱发性毛囊炎的患者,由于对多种免疫抑制药物和抗生素治疗无效,开始使用英夫利昔单抗治疗。在第二次输注英夫利昔单抗后,患者报告双侧腹股沟、阴茎、阴囊、会阴和肛周区域出现皮疹,与尖锐湿疣一致。该病例强调在开始抗TNF治疗前,尤其是使用英夫利昔单抗时,需要询问患者过去或当前的生殖器或肛门疣病史。如果存在,应考虑同时进行抗疣治疗。