University of Sydney, Sydney, New South Wales, Australia.
The Skin Hospital, Sydney, New South Wales, Australia.
Australas J Dermatol. 2020 Feb;61(1):54-56. doi: 10.1111/ajd.13178. Epub 2019 Oct 17.
Folliculitis decalvans is a neutrophilic cicatricial alopecia characterised by progressive pustular folliculitis. Folliculitis decalvans is seen as a condition usually limited exclusively to the scalp and rarely affects the limbs. We present a case of a 63-year-old man with a 3-year history of progressive pustular folliculitis with inflammatory patches and central scarring alopecia on both forearms and a circumscribed patch on his right lower leg. His presentation, clinical course and isolation of Staphylococcus aureus together with the histopathological findings all supported a folliculitis decalvans-like pustular folliculitis limited to the limbs. Biopsies revealed follicular pustules, gross interfollicular fibrosis with plasma cells and concentric perifollicular fibrosis with lymphocytes, all features seen with folliculitis decalvans. The positive response to antibiotics combined with topical corticosteroids mirrored the response seen with scalp folliculitis decalvans. In contrast to the previously reported cases, the patient had no evidence of folliculitis decalvans on the scalp.
脱发性毛囊炎是一种以进行性脓疱性毛囊炎为特征的中性粒细胞性瘢痕性脱发。脱发性毛囊炎通常被认为是一种仅限于头皮的疾病,很少累及四肢。我们报告了一例 63 岁男性患者,其前臂有 3 年进行性脓疱性毛囊炎病史,表现为炎症性斑块和中央瘢痕性脱发,右小腿有一个局限性斑块。他的表现、临床病程和金黄色葡萄球菌的分离,以及组织病理学发现均支持局限于四肢的脱发性毛囊炎样脓疱性毛囊炎。活检显示毛囊脓疱、粗毛囊间纤维化伴浆细胞、同心毛囊周围纤维化伴淋巴细胞,这些均是脱发性毛囊炎的特征。抗生素联合局部皮质类固醇的阳性反应与头皮脱发性毛囊炎的反应相似。与之前报道的病例不同,该患者头皮无脱发性毛囊炎的证据。